bacteria Flashcards
(54 cards)
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What are pyodermites?
Primary skin infections mainly caused by pyogenic bacteria (Staphylococcus, Streptococcus).
Name some resident bacterial flora of skin.
Micrococchi, S. albus, S. epidermidis, Corynebacterium acnes, Pityrosporum ovale, Candida albicans.
Name some transient (pathogenic) bacteria.
S. aureus, Streptococcus beta-hemolyticus, Pseudomonas aeruginosa.
How does resident flora protect skin?
Hydrolyzes lipids producing free fatty acids toxic to many bacteria.
List local factors favoring skin infections.
Alteration of hydrolipidic layer, stratum corneum reduction, maceration, topical therapies (corticosteroids, antibiotics).
What is bacterial superinfection?
Infection on previous lesions (dermatitis, wounds, trauma).
Most frequent bacteria in skin infections?
Gram+ Staphylococcus aureus, Streptococcus beta-hemolyticus group A.
Other bacteria involved in skin infections?
Pseudomonas aeruginosa, Escherichia coli, Enterobacter spp.
Diseases caused by Streptococcus pyogenes?
Impetigo vulgaris, erysipelas, cellulitis, scarlet fever.
Post-streptococcal complications?
Acute rheumatic fever, acute glomerulonephritis.
Diseases caused by Staphylococcus aureus?
Bullous impetigo, SSSS, folliculitis, abscess.
What are superficial non-adnexal forms of pyodermitis?
Impetigo, SSSS, scarlet fever, ecthyma.
Profound non-adnexal forms?
Erysipelas, infective cellulitis, necrotizing fasciitis, gas gangrene.
Adnexal forms?
Superficial and profound folliculitis, abscess, felon (whitlow).
Morphology of impetigo vulgaris?
Thin-walled pustule, ruptures to form honey-colored crust (meliceric).
Main cause of impetigo vulgaris?
Streptococcus (70% of cases).
Morphology of bullous impetigo?
Erythematous maculae progressing to superficial blisters and crusts.
Cause of bullous impetigo?
Staphylococcus aureus producing exfoliative toxins ETA, ETB.
What is Staphylococcal scalded skin syndrome (SSSS)?
Pediatric emergency with erythema, bullous lesions, epidermal detachment.
SSSS typical patient?
Infants, children; rarely immunosuppressed adults.
Systemic symptoms of SSSS?
Fever, malaise, crusting around mouth, nose, eyelids.
Pathogenesis of SSSS toxins?
ETA and ETB split desmoglein-1 in granular epidermis.
What causes scarlet fever?
Streptococcus pyogenes releasing pyrogenic toxin.