Bacterial Drug Guide Broken Down

Question 1

MOA of sulfonamides

Answer 1

• folate synthesis inhibitors

Question 2

sulfonamide drug to know

which are anti-pseudomonals

Answer 2

• sulfamethoxazole

Question 3

what drug do we combine sulfamethoxazole with

Answer 3

• trimethoprim

Question 4

MOA of flouroquinolones

Answer 4

• DNA damaging

- inhibit DNA gyrase

Question 5

fluoroquinolone drugs to know

which are anti-pseudomonals

Answer 5

• ciprofloxacin (anti-pseudomonals)
• levofloxacin (anti-pseudomonals)
• moxifloxacin
• gemifloxacin

Question 6

what are the two classes of cell wall synthesis inhibitors

Answer 6

• beta lactams

- glycopeptides

Question 7

what are the drug classes in the beta lactam class?

Answer 7

• penicillins
• monobactams
• carbapenems
• cephalosporins

MPCC Beta lactam

Question 8

broad spectrum penicillins to know

which are anti-pseudomonals

Answer 8

• ampicillin
• amoxicillin
• piperacillin (anti-pseudomonals)

Question 9

monobactam drugs to know

which are anti-pseudomonals

Answer 9

• aztreonam (anti-pseudomonals)

Question 10

carbapenem drugs to know

which are anti-pseudomonals

Answer 10

• imipenum (anti-pseudomonals)

- meropenum (anti-pseudomonals)

Question 11

cephalosporin drugs to know

which are anti-pseudomonals

Answer 11

• cefuroxime
• ceftriaxone
• cefotaxime
• cefpodoxime
• ceftazidime (anti-pseudomonals)
• cefepime (anti-pseudomonals)
• ceftaroline

Question 12

what drugs to combine with lactamase inhibitors?

Answer 12

• monobactams

- carbapenems

Question 13

lactamase inhibitors to know

which are anti-pseudomonals

Answer 13

• clavulanic acid

- tazobactam

Question 14

glycopeptides to know

which are anti-pseudomonals

Answer 14

• vancomycin

Question 15

what drug classes are protein synthesis inhibitors?

Answer 15

• 30S

- 50S

Question 16

what drug classes are 30S protein synthesis inhibitors?

Answer 16

• aminoglycosides
• tetracyclines

AT 30

Question 17

what drug classes are 50S protein synthesis inhibitors?

Answer 17

• macrolides
• oxazolidenones
• streptogramins
• lincosamides

50 is not SMOL

Question 18

aminoglycoside drugs to know

which are anti-pseudomonals

Answer 18

• gentamycin (anti-pseudomonals)
• tobramycin (anti-pseudomonals)
• amikacin (anti-pseudomonals)

Question 19

tetracycline drugs to know

which are anti-pseudomonals

Answer 19

• doxycycline

Question 20

macrolide drugs to know

which are anti-pseudomonals

Answer 20

• erythromycin
• clarithromycin
• azithromycin

MACRO ACE

Question 21

macrolides are pretty much effective against all gram positive except for which organism?

Answer 21

• H. flu

Question 22

oxazolidenone drugs to know

which are anti-pseudomonals

Answer 22

• linezolid

Question 23

lincosamide drugs to know

which are anti-pseudomonals

Answer 23

• clindamycin

Question 24

cell membrane disruptor classes of drugs

Answer 24

• polymyxin B

- daptomycin

Question 25

polymyxin B drugs to know which are anti-pseudomonals

Answer 25

- polymyxin E (colistin) (anti-pseudomonals)

Question 26

all folate synthesis inhibitors work against which organism class (gram+ or gram-)

Answer 26

- both

Question 27

all fluoroquinolones work against which organism class (gram+ or gram-)

Answer 27

- both

Question 28

all broad spectrum penicillins work against which organism class (gram+ or gram-)

Answer 28

- both

Question 29

all monobactams work against which organism class (gram+ or gram-)

Answer 29

- gram negative

Question 30

all carbapenems work against which organism class (gram+ or gram-)

Answer 30

- both

Question 31

most cephalosporins work against which organism class (gram+ or gram-) except which one (and what does it work against)

Answer 31

- both | - ceftazidime (gram negatives)

Question 32

all glycopeptides work against which organism class (gram+ or gram-)

Answer 32

- gram negatives

Question 33

all aminoglycosides work against which organism class (gram+ or gram-)

Answer 33

- both

Question 34

all tetracyclines work against which organism class (gram+ or gram-)

Answer 34

- both

Question 35

all macrolides work against which organism class (gram+ or gram-) except which organism in particular

Answer 35

- gram positive | - gram negative H. flu

Question 36

all oxazolidenones work against which organism class (gram+ or gram-)

Answer 36

- gram positives

Question 37

all lincosamides work against which organism class (gram+ or gram-)

Answer 37

- both

Question 38

all polyxmin B's work against which organism class (gram+ or gram-)

Answer 38

- gram negative