Basic GU Flashcards
What’s the chlamydia concordance rates between partners?
75%
What’s the spontaneous clearance rate of chlamydia?
50% by 12 months
How many a) men and b) women are symptomatic for chlamydia?
Men 60%
Women 20%
In MSM what are Chlamydia rates a) rectally b) pharyngeal?
A) rectal 3-10.5%
B) pharyngeal 0.5-2.3%
What % of LGV is asymptomatic?
26%
Chlamydia treatment: what to give if azithro and doxy contraindicated.
Erythromycin 500mg BD for 14 days
Or
Ofloxacin 200mg BD for 7 days
Chlamydia treatment in pregnancy
Azithromycin Or Erythromycin 50pmg qds for 7 days Or Amoxicillin 500mg tds for 7 days
Time frame for a) opthalmia neonatorum b) pneumonia?
A) 5-12 days
B) 1-3 months
What’s the cause of LGV?
Ct serovarse L1 L2 L3
L2 most common
Lgv incubation period?
3-30 days
Lgv lymphadenopathy follows the primary lesion by how many days?
10-30
Lgv treatment
Doxycycline 100mg bd 3 weeks Or Erythromycin 500mg qds 3 weeks Or Azithromycin 1g once a week for 3 weeks
What % of gonorrhoea–> PID or epididymo-orchitis
14%
When is a confirmatory test reccomended for positive gonorrhoea?
If the positive predictive value of a population on <90%
What % of patients with gonorrhoea will also have chlamydia?
19%
Gonorrhoea transmission risk after 1 episode of sex for man to woman. And reduction with condom use?
Man to woman 60-80%
Reduced by 40% with a condoms
Gonorrhoea transmission risk after 1 episode of sex for woman to man. And reduction with condom use?
Woman to man 20%
Reduced by 75% by condom use
What’s can be used for treatment for gonorrhoea (other than ceftriaxone) if sensitivity is known? And what’s the UK resistance rate to this?
500mg ciprofloxacin only if known susceptible. UK resistance is 36.4%
What are alternative gonorrhoea treatments?
Cefixime 400mg po
Gebtanicin 240mg im
Spectinomycin 2g im (+ azithromycin if pregnant)
Treatment for disseminated gonorrhoea infection? 4 options.
Then oral switch options
Ceftriaxone 1g im or iv every 24 hours Or Cefotaxime 1g iv every 8 hours Or Ciprofloxacin 500mg iv every 12 hours Or Spectinomycin 2g im every 12 hours
24-48 hours after symptoms improve can switch to oral:
Cefixime 400mg bd
Ciprpfloxacon 500mg bd
Ofloxacin 400mg bd
Total 7 day treatment
Whats the estimated prevalence of M Gen in the general population?
1-2%
M gen is seen in what % of a) NGU b) PID
Ngu: 15-25%
Pid: 10-13%
What % of m gen carriers are symptomatic? A men b) women
Men <10%
Women <5%
Whats the abstinence advice for M Gen?
14 days from starting treatment (and until symptoms resolve)
