Basic Knowledge

Question 1

What agency approves new test methodologies, instruments, and reagents before they are available for purchase by consumers?

Answer 1

Food and Drug Administration (FDA)

Question 2

How often should biological safety hoods be inspected?

Answer 2

Annually

Question 3

What is the minimum number of standards required for a standard curve?

Answer 3

3

Question 4

What is the maximum magnification using a brightfield micrscope?

Answer 4

1000X

Question 5

What is the most accuarte pipette for reconstituting control material?

Answer 5

Glass Volumetric Pipette

Question 6

Which unit of measure refers to 10^-3

Answer 6

Milli

Question 7

What is the calculated Cholesterol/HDL ratio given the following results?

Cholesterol: 225 mg/dL
HDL: 75 mg/dL

Answer 7

3

Question 8

200 ul of patient serum is diluted with 800 uL of saline. What is the final dilution?

Answer 8

1:5

Question 9

What is the calculated LDL cholesterol given the following lipid prolfile results?

Triglycerides:190 mg/dL
Cholesterol: 225mg/dL
HDL: 75mg/dL

Answer 9

112

Friedwald Equation:
Cholesterol-HDL+(Triglycerides/5)

Question 10

How is relative centrifugal force calculated?

Answer 10

1.18 X 10^-5 X r X rpm^2

Question 11

True or FalseTrue or False

A chain of custody is required for a pre-employment drug screen.

Answer 11

True

Question 12

True or FalseTrue or False

A chain of custody is required for a paternity test.

Answer 12

True

Question 13

True or FalseTrue or False

A chain of custody is required for a Fetal Fibronectin.

Answer 13

False

Question 14

What federal legislation regulates most clinical laboratories?

Answer 14

Clinical Laboratory Improvement Amendments
(CLIA)

Question 15

What is the level of complexity of most testing performed in clinical Laboratories

Answer 15

Moderately Complex

Question 16

How often does CLIA require clinical laboratories to have inspections?

Answer 16

Every 2 Years

Question 17

True or FalseTrue or False

Laboratories performing waived testing only are not required to participate in proficiency testing.

Answer 17

True

Question 18

True or FalseTrue or False

Laboratories performing moderately complex testing are not required to participate in proficiency testing.

Answer 18

False

Question 19

MultipleChoiceMultipleChoice

Which proficiency testing (PT) results do not meet the CLIA performance criteria?

A. Failed the same analyte in 2 consecutive PT events
B. Failed 2 analytes in 1 PT event
C. Failed 3 analytes in 1 PT event

Answer 19

A. Failed the same analyte in 2 consecutive PT events

Question 20

True or FalseTrue or False

Split samples sent to another facility using the same test method is an example of alternate proficiency testing.

Answer 20

True

Question 21

True or FalseTrue or False

Two technologists perform the same proficiency test is an example of alternate proficiency testing.

Answer 21

False

Question 22

True or FalseTrue or False

Mislabeling an add-on test is an example of a pre-analytical error.

Answer 22

True

Question 23

True or FalseTrue or False

Transcription error entering a manual result is an example of a pre-analytical error.

Answer 23

False

Question 24

MultipleChoiceMultipleChoice

Of the following, which is the most common analytical error?

A. Not checking specimen integrity
B. Mislabeling a specimen
C. Clerical errors
D. Reporting results outside the linear limits

Answer 24

Not checking specimen integrity

Question 25

What is the most common post-analytical error?

Answer 25

Clerical Errors

Question 26

How often must a procedure be reviewed?

Answer 26

Upon implementation and substantial revisions

Question 27

How often must thermometers be checked against the NIST thermometer?

Answer 27

Annually

Question 28

In which manual are the directions for running quality control for a specific assay kept?

Answer 28

Operating procedure manual

Question 29

Following equipment maintenance, when is quality control suggested?

Answer 29

After any preventative maintenance

Question 30

What is the most common reason for a control value to be outside of 3SD?

Answer 30

Random Error

Question 31

If one control is outside the 95% confidence limits, then what is the most appropriate remedial action to take initially?

Answer 31

Repeat the same control

Question 32

Where should an unopened container of methanol be stored?

Answer 32

Flammable safety cabinet

Question 33

After preventative maintenance by field service, what is recommended?

Answer 33

Verification of quality control results

Question 34

According to CLIA, who is responsible for specimen processing, test performance, and reporting test results?

Answer 34

Testing Personnel

Question 35

# *True or False**True or False*** Equipment Maintenance is not a job duty of the testing personnel.

Answer 35

False

Question 36

# *True or False**True or False*** Interpretation of highly complex testing is not a job duty of the testing personnel.

Answer 36

True

Question 37

# *True or False**True or False*** Graham Crackers are required to be kept in the employee's personnel records.

Answer 37

False

Question 38

# *True or False**True or False*** Remedial action documentationis required to be kept in the employee's personnel records.

Answer 38

True