Basic science Flashcards Preview

MSK > Basic science > Flashcards

Flashcards in Basic science Deck (16):
1

isotonic contraction
does tension or length stay constant?

tension constant

2

types of motor neurones in muscle spindle

gamma

3

skeletal muscle cell membrane

sarcolemma

4

which type of collagen in fibrocartilage

type 1

5

osteoprogenitor cells

pool of reserve osteoblasts

6

what do osteoblasts secrete?

osteoid

7

what hydrolyses Ach to terminate neuromuscular transmission

AchE

8

what is Lambert-Eaton Myasthenia syndrome assoc with

muscle weakness in limbs
SCC of lung

9

Skeletal NMJ
what causes fusion of Ach vesicles with presynaptic membrane?
what enters the cell when 2 mols of Ach bind and the gate opens?

Ca2+ causes fusion of Ach vesicles with the presynaptic membrane

2 mols of Ach bind, opening the gate, and Na+ enters the cell (K+ exits)

10

Myasthenia gravis
F or M?
25% have??

F
25% have thymoma

11

what does botulinum toxin irreversibly inhibit

Ach release

12

what do curare like compounds interfere with

post synaptic action of Ach

13

are TNF-alpha and IL1 involved in catabolism or anabolism?

catabolism

14

what cells produce and maintain the ECM

chondrocytes

15

property of proteoglycans

compressive
assoc with weight bearing

16

joint lubrication

hyaluronic acid
lubricin