bcm13

Question 1

purines

Answer 1

adenine

guanosine

Question 2

pyrimidines

Answer 2

cytosine
thymidine
uracil

Question 3

what are heterocyclic compounds?

Answer 3

compounds with one or more carbon atoms in ring

Question 4

draw cytosine

Answer 4

-

Question 5

draw thymine

Answer 5

-

Question 6

draw uracil

Answer 6

-

Question 7

what do purines have in common with histidine

Answer 7

imidazole ring

Question 8

draw adenine

Answer 8

-

Question 9

draw guanine

Answer 9

-

Question 10

nuceloside

Answer 10

base and ribose

Question 11

what are the 5 nucleosides

Answer 11

adenosine
guanosine
cytidine
uridine
thymidine

Question 12

nucleotides

Answer 12

base and ribose and phosphate

Question 13

draw amp

Answer 13

-

Question 14

what is dctp

draw

Answer 14

deoxycytidine triphosphate

- nucleotide with deoxy form of ribose`

Question 15

name two coenzymes that contain adenine

Answer 15

fad nad

Question 16

what is riboflavin?

Answer 16

vitamin b2

yellow compound used in practicles

Question 17

what is coA’s stucture

Answer 17

beta mercaptomethylamine (containing s) - panothenic acid - adp

Question 18

what can niacin definciency give you?

Answer 18

Pellegra- dermititis, diarrhoea, dementia

Question 19

what is nicotinic acid, draw

Answer 19

pyridine ring with carboxyllic acid at position 3

Question 20

what are the pkas of nicotinic acid

Answer 20

carboxylate 2.2

ring nitrogen 4.9

Question 21

draw cyclic amp

Answer 21

-

Question 22

what is amp?

Answer 22

adenosine 3’ 5’- cyclic monophosphate

Question 23

what does increase in camp concentration in cell do?

Answer 23

active protein kinases

Question 24

what does cyclic gmp act as?

Answer 24

an intracellular signalling molecule
- specialised functions in different types of cells
important in vision

Question 25

draw cyclic gmp

Answer 25

-

Question 26

how is cgmp synthesized?

Answer 26

from gtp by guanyl cyclase

Question 27

what does viagra do?

Answer 27

blocks break down of cGMP by cGMP phosphodiesterase

Question 28

what direction is dna sequence always specified in?

Answer 28

5' 3' direction of ribose

Question 29

what links nucleosides?

Answer 29

phosphodiester bridges

Question 30

what does negative charge of dna back bone prevent?

Answer 30

nucleophillic attack

Question 31

what are the watson and crick base pairs?

Answer 31

adenine and thymine | guanine and cytosdie

Question 32

draw out watson and crick base pairs

Answer 32

-

Question 33

what can happen to CG base pairs in vertebrates?

Answer 33

they can be methylated

Question 34

what is methyltion of dna bases in bacteria used to do?

Answer 34

block the action of restriction enzymes

Question 35

what is special about methylation of dna?

Answer 35

it can be inherited when a cell divides and can play a role in marking which genes are active

Question 36

what must a bacteria cell producing restriction enzymes also produce?

Answer 36

a methyl transferase to protect its own dna

Question 37

draw 5-methyl cytosine

Answer 37

-

Question 38

draw n methyl adenine

Answer 38

-

Question 39

what do bacteriophage use methylated dna to do?

Answer 39

recognise own dna and stop virus dna replication

Question 40

what do vertebrates use methylated dna for?

Answer 40

expression not protection

Question 41

what does dnap require?

Answer 41

template strand oglionucleotide primer supply of deoxynucleotide triphosphate dNTPs

Question 42

what does the 3' hydroxide act as?

Answer 42

a nucleophile

Question 43

what do chain terminators act as?

Answer 43

antiviral drugs - drugs for herpes no more bases can be added so virus cant replicate its dna

Question 44

why can hiv vaccine pass through membrane?

Answer 44

as the azido group is lipophillic

Question 45

what is udp glucose? | draw

Answer 45

precursor | uridine diphosphate glucose donates glucose for gycogen synthase

Question 46

what does ado met act as?

Answer 46

s-adenosylmethionine (SAM) acts as a methy donor

Question 47

what is the drug for herpes

Answer 47

acyclovir | contains guanine base

Question 48

what is the drug for hiv with an azido group | draw

Answer 48

azidothymidine (AZT) | contains thymidine with azido group on 3rd carbon

Question 49

what is the drug for hiv

Answer 49

zalcitabine dideoxycytosine cytosine attached to deoxy ribose

Question 50

what is an azido group?

Answer 50

-N=N^+=N^-

Question 51

what colour is fmn?

Answer 51

blue flavo mononucleotide

Question 52

what structure does riboflavin contain?

Answer 52

isoalloxazine ring