BCM30 Flashcards

(33 cards)

1
Q

synthatase

A

uses atp

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2
Q

synthase

A

no atp

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3
Q

phosphatase

A

removes phosphate

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4
Q

phosphorylates

A

add phosphate

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5
Q

kinase

A

cataylses transfer of phosphate groups

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6
Q

how is ammonia assimilated

A

via glutamine synthetase

glutamate + NH3 + ATP ->glutamine

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7
Q

glutamate synthase

A

alpha keto gluterate -> glutamate

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8
Q

what do transaminases do?

A

transfer NH2 from aa to alpha keto acids
with pyridoxal phosphaate
swap nh3 for cooh
glutamate + oxaloacetate +glutamate -> alphaketogluterate + aspartate

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9
Q

what is the keq for most transaminases?

A

1

used both catabolically and anabolically

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10
Q

what do all areas with food production in the world?

A

1 legume

1 grass

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11
Q

what does glutamate dehydrogenase do?

A

deaminates glutamate freeing ammonia
glutamate alpha keto gluterate
reductive removal of ammonia from

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12
Q

why cant glutamate dehydrogenase be used to assimilate ammonia in plants?

A

because the km (NH3) for gs = 10um

and gdh = 20mm

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13
Q

pga transamination

A

serine

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14
Q

pep transamination

A

-

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15
Q

pyruvate transamination

A

alanine

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16
Q

akg transamination

17
Q

oxaloacetate transamination

18
Q

ribose p transamination

19
Q

pga modification of c skel

A

glycine

cysteine

20
Q

pep modification of c skel

A

tyrosine
phenylamine
tryptophan

21
Q

pyruvate modification of carbon skeleton

A

valine

leucine

22
Q

akg modification of carbon skeleton

A

glutamine
proline
arginine

23
Q

oxaloacetate modification of carbon skel

A
aparagine
lysine
threonine
methione
isoleucine
24
Q

ribose p modication of carbon skel

25
what does urea look lik
CO(NH2)2
26
what is the only new enzyme required in the urea cycle
arg->urea evolved from krebs not just catabolic also anabolic forms arginine
27
what happens if excess purine in diet
-> uric acid -> allanine via uricase | primates lack uricase so goes to uric acid which can form crystals and gout
28
what is allanoin
soluble used in cosmetics
29
desrcibe ureotellic excretion
``` urea animals limited water less toxic, highly soluble mammals and sharks*used for osmoreg aatp/n ```
30
describe ammoniatellic excretion
``` ammonia large excess water highly toxic through gills bony fish and most invertebrate - woodlouse ```
31
describe uricotellic excretion
``` uric acid very limited water access insoluble solid birds reptiles insets monotremes dalmations 2atp/n ```
32
how do amphibians excrete urea
by simple diffusion
33
what could have led to rise of the dinosaurs
uricotellic excretion | useful in permian with limited water acess