Bighead

Question 1

Definition

Answer 1

As a histotoxic disease مهمة , infectious disease of rams, occur in head

Question 2

Caused

Answer 2

by the toxin of Cl. novyi type A and

Question 3

Characterized by

Answer 3

inflammatory edema of the head and neck.

Question 4

Clostridium novyi species

Answer 4

Cl. novyi A = Bighead - histotoxic disease
Cl. novyi B = Black disease - Enterotoxiemia
Cl. novyi C = Osteomyelitis in buffalo - histotoxic disease
Cl haemolyticum (Cl. novyi D) = Bacillary hemoglobinuria - Enterotoxiemia

Question 5

Pathogenesis

Answer 5

Short course, During ram fights, soil-borne spores are driven into the skin and produce toxins that cause necrosis. Then, they enter the bloodstream, causing toxemia and fluid accumulation . Bacterial toxins increase capillary permeability in the head and neck regions, leading to pronounced inflammatory edema, followed by shock.

Question 6

Postmortem lesion

Answer 6

Black tissue , edema

Question 7

Differential Diagnosis

Answer 7

Bighead, malignant edema, snake bite

Question 8

Treatment

Answer 8

Penicillin

Question 9

Prevention and control

Answer 9

Prevent fighting, vaccine