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Flashcards in bio chapter 9 Deck (28):
1

Which one of the following is NOT a cell surface-type receptor?

steroid receptor

2

What determines the specificity of a receptor protein

the ligand-binding site

3

Many pathologies are the result of a problem with cell signaling. Which of the following pathologies best exemplifies this fact?

Cancer, caused by a truncated receptor that is now stuck in the activated form

4

What does a ligand-gated channel

It allows for the movement of ions across the plasma membrane

5

Why dont steroid hormones bind to transmembrane cell-surface receptors?

steroid hormones are nonpolar and will cross the cell's plasma membrane, binding to receptors inside the cell

6

A researcher is using a small molecule inhibitor to manipulate a signaling pathway. This inhibitor prevents phosphorylation and most likely targets a :

receptor kinase

7

Given that most ligands form covalent bonds with their associated receptors, these complexes are more-or-less permanent and can only be broken through the use of ATP

FALSE

8

Notch and Delta are both transmembrane proteins, involved in cell communication in the developing nervous system of vertebrate animals. What makes Notch different from Delta

Notch is a receptor and Delta is a signaling molecule

9

Which one of the following initiates signal termination

The release of signal molecules from their receptors

10

Which of the following is NOT a true statement about receptors that are localized to the nucleus?

They bind polar ligands

11

How does an "activated" receptor transfer information into the cell

through a conformation change

12

Why dont steroid hormones bind to transmembrane cell-surface receptors

steroid hormones are nonpolar and will cross the cells plasma membrane, binding to receptors inside the cell

13

Which one of the following initiates signal termination

the release of signal molecules from their receptors

14

Which of the following is not a true statement about receptors that are localized to the nucleus

they bind polar ligands

15

In cell communication, which one of the following is a requirement of the responding cell?

it must have receptor proteins

16

Where would you expect to find the receptor for a nonpolar ligand?

either in the nucleus of the cell or in the cytosol

17

To what does the term ligand refer to?

a signaling molecule

18

Which type of protein adds a phosphate group to another molecule

kinase

19

signal transduction results in:

A response by the cell

20

Growth factors such as platelet-derived growth factor function in:

paracrine signaling

21

Which of the following is NOT an essential element involved in communication between all cells?

transduction element

22

Which of the following is a cellular response to signal transduction

**a change in the proteins found in the cytosol
**the release of more cytosol signal molecules
**a change in the activity of an enzyme

23

Which if the correct order for these stages in cell signaling?

receptor activation, signal transduction, response

24

Endocrine signaling is

Through the bloodstream far away

25

Autocrine signaling is

Same molecule

26

Paracrine symboling is

Very close molecules

27

Juxtacrine signaling is

Connected cells

28

The oxygen produced in photosynthesis comes from water, not carbon dioxide

.