Flashcards in bio chap 13 Deck (24)
False statements about sequence motifs
Sequence motifs are only found in DNA―they do not occur in RNA.
When sequence motifs occur in DNA, they are only found upstream of protein-coding regions.
All sequence motifs would also be considered open reading frames, but not all open reading frames would be considered sequence motifs.
Sequence motifs in RNA do not provide any information on possible sequence motifs in DNA.
The human chromosome 1 is approximately 250 million nucleotides long. In order to sequence human chromosome 1, the chromosome is digested into hundreds of small fragments. These short fragments are placed together in the correct order to generate the long, continuous sequence of nucleotides in chromosome 1. Placing these fragments together is referred to as:
The C-value paradox is the:
disconnect between genome size and organismal complexity.
In the eukaryotic DNA sequence below, which type of repeat is highlighted?
What was the goal of the Human Genome Project?
sequencing every gene in the human cell
The region of DNA sequences before the start of a gene is often called the promoter. One type of promoter is called the TATA box. Many species' promoters are TATA boxes or a variation of the TATA box. DNA sequences that are similar in different organisms are called _______________ sequences.
Transposable elements are:
DNA sequences that can insert themselves into new positions within the genome
DNA transposable elements (DNA TEs) are:
a class of transposable elements that replicate and transpose via DNA replication and repair.
Whenever a genome is annotated, researchers identify all of the protein-coding genes and assign each protein with a function.
Only 2.5% of the human genome actually codes for proteins. The other 97.5% includes:
Having more than two sets of chromosomes in the genome called:
All of the following are ways we account for the disconnect between levels of complexity and gene number between organisms EXCEPT:
All of the answer options are reasons for the disconnect between complex and less complex organisms.
different gene products are made in different amounts.
proteins are capable of combining in many different ways to perform different functions.
a single gene may yield different proteins due to alternative splicing.
Imagine that a researcher is comparing the sequence of several protein-coding genes between mice, rabbits, and humans. She finds that, for most of these genes, the rabbit sequences are more similar to the human sequences than are the mouse sequences. What can she deduce?
More sequences are conserved between rabbits and humans than between humans and mice.
long terminal repeats (LTRs) are:
a class of transposable elements that uses RNA as an intermediate.
Repeated sequences within eukaryotic genomes may be represented as long repeated sequences next to each other, and are called ___________ repeats. Repeated sequences in eukaryotic genomes can also be located throughout the genome, and are called _______________ repeats.
Repeated sequences make DNA sequencing challenging for of all of the following reasons EXCEPT:
the long repeats often have mutations that are not easily sequenced.
Whole genome sequencing is often approached by a shotgun sequencing approach in which:
large genomes are randomly digested, short fragments are sequenced, and the overlapping sequences are assembled in order.
Which of the following is not a type of sequence identified by gene annotation?
Which of the following statements is true regarding a genome?
Genomes are "heritable," or passed from parents to offspring.
Which of the following are sequence motifs?
open reading frame
The human genome is different for every individual.
Knowing an individual's DNA sequence may be beneficial because:
it makes it possible to predict susceptibility to disease.
it makes it possible to predict response to medications.
it makes it possible to predict physical differences.
it makes it possible to predict the occurrence of a disease.
Sequence assembly is accomplished by
aligning the fragments by using a complex computer program.