BIOCHEMISTRY Flashcards

(49 cards)

1
Q

It is the study of the compounds and chemical changes that are brought about by living processes.

A

BIOCHEMISTRY

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2
Q

The process by which polar solute is broken down into its individual ionic components by the action of solvent (water).

A

IONIZATION / DISSOCIATION

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3
Q

Substances which are completely ionized in water solution.

A

STRONG ELECTROLYTES

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4
Q

Substances whose aqueousbsolution conducts electricity.

A

ELECTROLYTES

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5
Q

Substances which are incompletely or partially ionized in water solution.

A

WEAK ELECTROLYTES

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6
Q

Substances which are non-conductors of electricity even in the molten state.

A

NON-ELECTROLYTES

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7
Q

A reaction which does not go to completion; products can’t form back reactants.

A

IRREVERSIBLE REACTION

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8
Q

A reaction which goes to completion and products can still react to form back the reactants.

A

REVERSIBLE REACTION

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9
Q

A state at which teo opposing reactions proceed at the same rate.

A

CHEMICAL EQUILIBRIUM

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10
Q

It is a partial reversible ionization.

A

WATER EQUILIBRIUM / IONIZATION OF WATER

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11
Q

It is a mixture of a weak electrolyte an its salt; resists an abrupt or drastic change in pH even upon the addition of either a strong acid of strong base.

A

BUFFER / BUFFER SOLUTION

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12
Q

Process in the central dogma of molecular biology.

A

DNA πŸ‘‰πŸ» RNA πŸ‘‰πŸ» PROTEIN

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13
Q
  • produces all the proteins an organism requires
  • Transcription of DNA: RNA copy a small section of a chromosome
  • Translation of RNA: protein synthesis
  • occurs throughout interphase
  • transcription in nucleus
  • translation in cytoplasm
A

GENE EXPRESSION

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14
Q
  • duplicates the chromosomes before cell division
  • DNA copy of entire chromosome
  • occurs during S phase
  • replication in nucleus
A

DNA REPLICATION

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15
Q

It produces DNA copies of an RNA; more commonly associated with the life cycle of retroviruses

A

REVERSE TRANSCRIPTION

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16
Q

Where do nucleic acids are assembled?

A

NUCLEOTIDES

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17
Q

It consists Five Carbon Sugar (Ribose & Deoxyribose), Nitrogen containing bases and Phosphate.

A

NUCLEOTIDES

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18
Q

Adenine and Guanine are called??

A

PURINES

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19
Q

Cytosine, uracil and thymine are called??

A

PYRIMIDINES

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20
Q

It is formed by covalently linking a base to the number 1 carbon of a sugar.

21
Q

It is formes when one or more phosphate group is attached to the 5’ carbon of a nucleoside.

22
Q

Polymers of nucleotides linked by 3’ , 5’ phosphodiester bonds.

A

NUCLEIC ACIDS

23
Q

A) two strands are antiparallel (opposite direction)
B) two strands are complementary. A always pairs with T (two H-bond), and G always pairs with C (three H-bond). Thus, the base sequence on one strand defines the base sequence on the other strand.

A

DNA STRUCTURE

24
Q

Because of the specific base pairing, the amount of A equals the amount of T. Thus, total purines equals total pyrimidines.

A

CHARGAFF’S RULE

25
Most DNA occur in a right-handed doubled-helical molecule.
WATSON-CRICK DNA or B-DNA
26
Twisting of DNA around itself in three-dimensional space. It results from the strain caused by under- or overwinding the double helix.
SUPERCOILING
27
It changes the amount of supercoiling in DNA molecules.
TOPOISOMERASES
28
Packaging unit of the chromatin. It contains nuclear DNA associated with histones (H2a, H2b, H3, H4) and non-histone proteins.
NUCLEOSOME
29
Cells in interphase contain what two types of chromatin?
EUROCHROMATIN and HETEROCHROMATIN
30
Its a chromatin which is loosely packaged and transcriptionally active.
EUROCHROMATIN
31
It is a chromatin which is tightly packaged and inactive.
HETEROCHROMATIN
32
Steps involved in DNA replication
- Recognition of origin of replication - unwinding of DNA double helix - stabilization of unwound template strands - synthesis of RNA primers - synthesis of DNA - leading strand - logging strand (Okazaki fragments) - removal of RNA primers - replacement of RNA with DNA - joining of OF - removal of positive supercoils ahead of advancing replication forks - synthesis of telomeres
33
- Most abundant type of RNA - Structural component of the ribosome - Associates with ribosomal proteins to form the complete, functional ribosome
Ribosomal RNA
34
- 2nd most abundant | - carry amino acids to the ribosome, where they will be linked together during protein synthesis
Transfer RNA
35
- carries information specifying the amino acid sequence of a protein to the ribosome - only type of RNA that is translated - very heterogeneous in size and base sequence
Messenger RNA
36
A nucleotide sequence in an mRNA molecule specifies the amino acid sequence of a protein
TRANSLATION
37
A subunit of ribosomes which is a binding site for mRNA
SMALL SUBUNIT
38
It is a subunit of ribosome which is two binding sites for tRNA molecules.
LARGE SUBUNIT
39
Level of protein's structure which the number and types of amino acids in the specific amino acid sequence.
PRIMARY
40
Level of protein's structure which regularly repeating structures stabilized by H-bonds bet. amino acids w/in the protein.
SECONDARY
41
Level of protein's structure which the overall shape, or conformation, of the protein molecule
TERTIARY
42
Level of protein's structure which the shape or structre that results from interaction of more than one protein molecule, or protein subunits held together by noncovalent forces.
QUATERNARY
43
Most proteins are synthesized where?
LIVER
44
Immunoglobins are synthesized by...?
PLASMA CELLS
45
It is the only carbohydrate to be used directly for energy.
GLUCOSE
46
Any compound produce by a cell, which is binding to its receptor, alters the metabolism of the cell bearing the hormone-receptor complex.
HORMONES
47
Hormone binds to receptor of the CELL THAT PRODUCES THEM
AUTOCRINE
48
Hormone binds to receptor of a CELL NEARBY
PARACRINE
49
Hormone binds to reeptor of a CELL AT A DISTANT SITE
TELECRINE