Bioenergetics Flashcards

(58 cards)

0
Q

What is bioenergetics?

A

Flow of energy in a biological system: macronutrients into biologically useable energy. (food/chemical energy into muscle contraction/mechanical energy)

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1
Q

Exergonic vs. endergonic reactions

A

Exergonic: releases energy; usually catabolic

Endergonic: requires energy; usually endergonic

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2
Q

3 basic biological energy systems

A

1) phosphagen
2) glycolysis
3) oxidative systems

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3
Q

Anaerobic process

A

Do not require the presence of oxygen

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4
Q

Aerobic process

A

Process that depends on oxygen

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5
Q

Kreb cycle, electron transport chain, and rest of the oxidative system

A

Aerobic mechanisms that occur in the mitochondria

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6
Q

Which macronutrients are essential to anaerobic metabolism and why?

A

Carbohydrates: metabolized for energy with out oxygen involvement

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7
Q

Creatine phosphate

A

High energy molecule involved in the phosphagen system. Hydrolysis of this molecule provides a phosphate group to combine with ADP

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8
Q

Law of mass action or mass action effect

A

The concentration of reactants and/ or products in solution will drive the direction of the reaction

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9
Q

Glycolysis

A

The break down of carbohydrates; anaerobic. Less rapid than creatine kinase but higher capacity of ATP

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10
Q

What 2 things can happen with pyruvate?

A

1) fast glycolysis: converted to lactate and used for anaerobic ATP resynthesis
2) taken to mitochondria and undergoes the keen cycle (slower and used for longer duration)

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11
Q

Gluconeogenesis

A

The formation of glucose from noncarbohydrate sources- during extended exercise and recovery

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12
Q

true or false: the process of pyruvate to lactate results in the formation of lactic acid.

A

False.

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13
Q

lactate production increases with…

A

increased exercise and type II muscle fibers

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14
Q

Lactate clearance

A

3 ways: lactate can be oxidized in the muscle it was produced in or transported by the blood to another muscle to be oxidized OR taken to liver where it is converted into glucose

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15
Q

Cori Cycle

A

cycle of: blood glucose taken to the muscle- lactate in muscle- blood transports lactate to liver - converted to glucose in the liver- taken back by way of the blood to muscle

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16
Q

Phosphorylation

A

process of adding an inorganic phosphate to another molecule. (ADP+P=ATP)

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17
Q

Oxidative Phosphorylation

A

resynthesis of ATP in the electron transport chain

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18
Q

Substrate Level Phosphorylation

A

direct resynthesis of ATP from ADP during a single reaction in the metabolic pathways.

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19
Q

What are the 2 primary mechanisms for ATP resynthesis during metabolism

A

Substrate-level phosphorylation and

Oxidative phosphorylation

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20
Q

What is the net gain of glycolysis (using blood glucose)? Explain

A

2 ATP are required to power glycolysis and 4 are resynthesized: net gain of 2

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21
Q

What is the net gain of glycolysis (using muscle glycogen)? Explain

A

1 ATP is required to power glycolysis and 4 are resunthesized: net gain of 3

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22
Q

What factors stimulate glycolysis?

A

High concentrations of ADP, decrease in pH levels and AMP

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23
Q

What must be the conditions for pyruvate to be transported to the mitochondria? What happens next?

A

If oxygen levels are high enough (exercise intensity is low enough/ athlete is conditioned) then pyruvate is converted to Acetyl CoA and undergoes the Kreb cycle.

24
the oxidative system is the primary system when...
the body is at rest or at low intensity, long endurance exercise
25
What is oxygen deficit?
up to the first 4 minutes of exercise the body's energy systems require a higher oxygen level then the body is able to provide. Oxygen uptake increases rapidly during this time until the body reaches steady state
27
name 3 important glycolytic enzymes
hexokinase phosphofructokinase pyruvate kinase
28
Energy
capacity to perform work
29
Catabolic reactions
breakdown of large protein/fat/carbohydrate molecules into smaller products "yielding energy release"
30
Anabolic reactions
The formation of large molecules from small protein/fat/carbohydrate substrates *requiring energy*
31
Why can't we sprint indefinitely?
The processes required for different activities differ in duration. Fast powerful activity requires ATP at a higher rate then slower longer duration activities (Anaerobic vs. aerobic). Anaerobic processes cannot last as long as long
32
Metabolism
the total of all the reactions that take place in the cells of the body
33
coupled reactions
the energy given off by exergonic reactions powers an endergonic reaction
34
ATP
bioenergy currency of all cells
35
Energy
capacity to perform work
36
Catabolic reactions
breakdown of large protein/fat/carbohydrate molecules into smaller products "yielding energy release"
37
Anabolic reactions
The formation of large molecules from small protein/fat/carbohydrate substrates *requiring energy*
38
Why can't we sprint indefinitely?
The processes required for different activities differ in duration. Fast powerful activity requires ATP at a higher rate then slower longer duration activities (Anaerobic vs. aerobic). Anaerobic processes cannot last as long as long
39
Metabolism
the total of all the reactions that take place in the cells of the body
40
blood lactate concentrations reflect...
lactate production and clearance
41
ATP
bioenergy currency of all cells
42
energy is stored between the ...
2nd and 3rd phosphate groups
43
true or false: all energy systems are always active but in different proportions.
true
44
which muscles contain the highest concentrations of creatine kinase?
IIx
45
what determines the fate of pyruvate?
presence or absence of oxygen
46
Lactate Dehydrogenase
enzyme the catalyzes the formation of lactate
47
blood lactate concentrations reflect...
lactate production and clearance
48
How does H+ effect muscle contraction?
3 Mechanisms: - enzyme activity - actin/myosin binding affinity - O2 carrying capacity for hemoglobin
49
OBLA
Onset of Blood Lactate Accumulation: when the blood lactate concentration reaches 4 mmol/L
50
What does OBLA reflect
body's clearance capacity
51
LT
Lactate Threshold
52
What is LT?
point when lactate levels abruptly rise above baseline concentration (body must be working anaerobically. high lactate concentration reflect and perpetuate glycolysis)
53
What determines oxidative capacity?
1) oxidative enzyme levels 2) muscle fiber type composition 3) oxygen availability
54
Cardiorespiratory Endurance
Ability of whole body to sustain prolonged exercise
55
where does the phosphagen system take place?
sarcoplasm of the muscle cell
56
where does the kreb cycle take place?
mitochondria
57
where does glycolysis take place?
sarcoplasm of the cell
58
Define VO2 Max
The maximum capacity of an individual's body to transport and use oxygen during exercise. Also called maximum aerobic capacity