biomolecules Flashcards

(74 cards)

1
Q

polarity

A

distribution of charge within a molecule due to differences in electronegativity between atoms

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2
Q

functional groups

A

specific group of atoms that contribute to a predictable behavior of the molecule

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3
Q

most polar type of molecules

A

ones with charges like carbonic acid and NH3+

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4
Q

steroids

A

cholesterol derived non-polar hormones. consist of 4 hydrocarbon rings

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5
Q

amphipathic molecules

A

molecule with significant polar and nonpolar regions
ex: fatty acids

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6
Q

what kinds of solvents are physiologically toxic?

A

nonpolar solvents like hexane

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7
Q

what kind of compounds are lipophilic?

A

hydrocarbons (alkanes,alkenes, alkynes)

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8
Q

structure of an amino acid

A

an amino group, hydrogen, R group, and cooh group bound to a central carbon

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9
Q

what part of the amino acid determines its properties?

A

r group

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10
Q

r group classifications

A

positively charged, negatively charged, polar, nonpolar

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11
Q

which amino acid is achiral

A

glycine

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12
Q

which amino acids are aromatic

A

tyrosine, tryptophan, phenylalenine

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13
Q

which amino acids contain sulfur?

A

met and cyst

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14
Q

which amino acid breaks up secondary structure

A

proline (formation of proline kinks)

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15
Q

nonpolar amino acids

A

G, A,V, I, L, M, P, F, Y, W

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16
Q

polar amino acids

A

S, T, N, Q, C

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17
Q

positively charged amino acids?

A

R, K, H

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18
Q

negatively charged amino acids?

A

D, E

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19
Q

which amino acid is responsible for the formation of disulfide bridges in terciary protein structure?

A

cysteine- cystine

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20
Q

what bond joins amino acids to make proteins?

A

peptide bonds (dehydration)
- between cooh of previous amino acid and NH3 of next amino acid

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21
Q

direction of proteins

A

N terminus to C terminus

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22
Q

primary protein structure

A

sequence of amino acids, unchanged following denaturation

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23
Q

secondary protein structure

A

hydrogen bonding between the amine and cooh groups in the amino acid backbone that create alpha helicies and beta sheets

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24
Q

terciary structure

A

interactions between side chains, all proteins have this structure

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25
quartenary protein structure
not all proteins possess this structure, interactions between multiple peptide subunits
26
lipids functions
storage, energy, structure, signalling
27
types of lipids
1. fatty acids + derivatives 2. cholesterol + derivatives 3. eocosinoids (prostaglandins) 4. terpenes and terpenoids
28
fatty acids
long chain carboxylic acids, can be branched or unbranched
29
TAGs
3 fatty acids bonded to a glycerol backbone. important for fat storage. bond can be broken via saponification
30
phospholipids
derivative of TAGS 2 fatty acids and a p group bound to glycerol. most common lipid in membrane
31
spingolipid
sphingosine bound to a fatty acid
32
waxes
naturally occuring mixtures of lipids that include fatty acids, long-chain fatty alcohols, aromatic compounds. secreted by plants
33
cholesterol
precursor for vitamin d and steroids, 4 hydrocarbon rings. nonpolar and important in signalling
34
eocosinoids (prostaglandins)
derived from arachodonic acid, important in signalling and controlling inflammation
35
terpens/ terpenoids
hydrocarbons composed of repeating isoprene (C5H8) units - ex: squalene - precursor for vitamin A
36
squalene
terpene precursor of cholesterol
37
fat soluble vitamins
A, D, E, K
38
carbohydrates
major source of energy, composed of C(h2O) units with at least one carbonyl and one hydroxyl group
39
aldose sugar
sugar where the carbonyl is terminal ex- glucose
40
ketose sugar
sugar where the carbonyl is inside the chain (not terminal ) ex- fructose
41
what isomer do carbs exsist in?
D
42
which configuration do amino acids exsist in ?
L
43
fructose
ketohexose that is made by plants and found in fruits
44
galactose
aldohexose epimer of glucose
45
sucrose
glucose and fructose (alpha 1-4)
46
maltose
glucose + glucose
47
lactose
glucose + galactose
48
amylose
linear polysaccharide linked by a(1-4) bonds - major component of starch
49
amylopectin
branched polysaccharide linked by a 1-4 and branches a 1-6 bonds - makes up majority of starch and is easily broken down
50
starch
major storage polysaccharide in plants. composed of amylose and amylopectin - most common carbohydrate in diet q
51
glycogen
animal carbohydrate storage with a1-4 and branched 1-6 synthesized in liver and stored in liver and muscle
52
cellulose
structural polysaccharide made by plants b1-4 bonds that cannot be digested by humans - makes up dietary fiber
53
nucleic acid functions
store and transmit genetic information
54
nucleotide
made of nitrogenous base, phosphate group, and 5 carbon sugar (pentose)
55
nucleoside
nitrogenous base and pentose
56
nitrogenous bases
A, T, G, C, U
57
purines
2 ring structure A and G
58
pyrimidines
1 ring structure T, C, U
59
structural significance of uracil
demethylated version of thymine
60
difference between RNA and DNA pentose?
ribose has a 2' OH group while DNA pentose is missing 2' OH
61
bond that connects phosphate group and pentose sugar in nucleic acids ?
phosphodiester bond between phosphate of previous group and pentose of next group adds a p group to the 3' end
62
which direction are phosphodeister bonds made
5' to 3'
63
how many hydrogen bonds are formed between A and T
2
64
how many hydrogen bonds are formed between g and C
3
65
what keeps the two strands of DNA together in a double helix
hydrogen bonding between nitrogenous bases
66
DNA double strands are..
antiparallel one is 5'-3' other is 3'-5'
67
b DNA
most common type 10 bases per turn
68
A- DNA
tighter than regular dna with 11 bases per turn
69
z DNA
loser with 12 bases per turn
70
subtypes of DNA
mitochondrial DNA
71
subtypes of RNA
mRNA, tRNA, r RNA, miRNA, siRNA, hnRNA
72
18 of the 19 amino acids that are chiral are S orientation.. which amino acid is the exception?
L-cystine is R oriented
73
how do double bonds effect the boiling point of fatty acids
unsaturation will lower boiling point
74
which type of character increases boiling point of fatty acids? trans or cis
trans