Block 2 Flashcards
(21 cards)
What does “M” stand for?
Mix
What does Ft stand for
make
BUD for non-H2O non-sterile compounded products?
6 months
BUD for non-oral, aqueous non-sterile compounded products?
30 days
BUD for oral, aqueous non-sterile compounded products?
14 days
What must be included in the labeling of non-sterile compounded product?
1) notification of a compounded product
2) BUD & storage
What should be included in the education materials upon dispensing of a non-sterile compounded product?
1) OBRA 90 Requirements
2) storage/handling/disposal
3) ADR reporting
4) changes in physical characteristics
What are glass mortars used for?
1) staining / potent drugs
2) preferred for liquids / semi-solids
What are the considerations for use of a glass mortar?
1) no emulsions
2) nothing hard – no glass spatula!
What is a wedgewood mortar used for?
1) emulsions
2) grinding or crystals / large particles
What are the considerations for use of a wedgewood mortar?
1) it is porous – no staining or potent drugs
What is a porcelain mortar used for?
Same as wedgewood, but less expensive.
1) emulsions
2) grinding or crystals / large particles
What are considerations for use of a porcelain mortar?
1) it is porous – no staining or potent drugs
2) less durable than wedgewood
Methods for comminution?
1) pulverization by intervention
2) eutectic mixtures
3) levigation
4) trituration
What does comminution mean?
reduction of particle size
What are the methods of blending?
1) spatulation
2) trituration
3) tumbling
How is levigation different from spatulation?
Grinding in levigation gets particle size reduction.
Describe trituration.
a circular motion in the mortar & pestle achieving particle size reduction by outward & inward circles. Powders are removed from side of mortar with rubber spatula
Describe levigation
A mass of solid is formed by addition of minimal liquid. Grinding. In pestle or on ointment slab
Describe spatulation.
Move spatula through powders on an ointment slab or in mortar;; no particle size reduction is achieved
What are the considerations for adding a drug to formulary?
1) indication & clincal utility
2) dosing interval
3) mechanism of action
4) dosage forms
5) ADRs, C/Is
6) Age restriction
7) Cost
