Block 3 Development Flashcards
(53 cards)
What are the components of the somatopleure?
The splanchnopleure?
Somatopleure = Superficial ectoderm + somatic mesoderm
Splanchnopleure = Endoderm + splanchnic mesoderm
The somatic layer of mesoderm forms the _____ layer of pleura, pericardium & peritoneum while the splanchnic layer forms the _____ layer.
Somatic - parietal (GSA)
Splanchnic - visceral (GVA)
What are the three coelomic/body cavities present after 4 weeks of development
Pericardial cavity
Peritoneal cavity
Pericardioperitoneal canals
The pericardial and peritoneal cavities are separates by the _____
Septum transversum
The pleura and pericardium are separated by the _____
Pleuro-pericardial membranes
The central tendon of the diaphragm arises from the _____
Septum transversum
The muscular component of the dorsal mesentery of the esophagus forms what part of the diaphragm?
The crura on either side of the aortic hiatus
The peripheral portions of the diaphragm are formed from _____
The abdominal (body wall)
What positionis the diaphragm at at 4 weeks? 6 weeks? 8 weeks?
4th week: Opposite 3rd, 4th, 5th cervical somites
6th week: Level of thoracic vertebrae
8th week: Level of L1
A congenital diaphragmatic hernia, forming a Foramen of Bochdalek, is a posterolateral defect resulting from the failure of _____.
Pleuroperitoneal membrane fusion
A severe consequence of a congenital diaphragmatic hernia is _____
Pulmonary hypoplasia (Not enough room for lung to develop properly)
Also causes mediastainal deviation (displacement of organs away from the hernia)
_____ is a condition where the esophagus ends as a blind tube. It results in polyhydramnios.
Esophageal atresia
_____ is a condition that results in a connection between the esophagus and trachea. This results in aspiration of fluid, and air in the stomach.
Esophageal fistula
A congenital hiatal hernia is the result of an _____. The esophagus will herniate through its hiatus.
Esophagus that is too short
The stomach forms from a dilation in the _____ in the 4th week.
Caudal part of foregut
The developing stomach is suspended from the posterior abdominal wall by _____
Dorsal mesentery (Dorsomesogastrum)
The dorsal part of the developing stomach will form the _____, while the ventral part will form the _____
Greater curvature
Lesser curvature
The 90 degree rotation of the stomach in development has what consequences?
Hint: there are four
Dorsal border moves to left side
Ventral border moves to right side
Left vagus nerve becomes anterior vagal trunk
Right vagus nerve becomes posterior vagal trunk
The dorsal mesentery of the stomach goes on to form the _____
Greater omentum
_____ is the result of a hypertrophy of the pyloric sphincter. What giveaway symptom would be present in this condition?
Hypertrophic pyloric stenosis
Projectile non-bilious vomiting
What gives the duodenum its characteristic C-shape?
90 degree rotation to the right in development
The first part of the duodenum is _____ while the 2nd, 3rd, and 4th part is _____
1st part - intraperitoneal
2nd, 3rd & 4th part - Secondary retroperitoneal
Duodenal stenosis occurs when _____, while duodenal atresia occurs when _____
Stenosis - Duodenum doesn’t recanalize enough
Atresia - Duodenum doesn’t recanalize at all
What kind of vomiting would you expect in duodenal stenosis or atresia?
Bilious vomiting (obstruction is distal to entrance of common bile duct)
