block d lecture 1 Flashcards

1
Q

what do astrocytes connect with

A

neurons and blood vessels
BBB

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2
Q

what wraps around axon

A

myelin sheath

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3
Q

what do myelin sheaths do

A

increase speed of action potential conduction

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4
Q

as found in a recent development what forms during learning of a new motor skill

A

oligodendrocyte

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5
Q

3 major subdivisions of the brain

A

forebrain
midbrain
hindbrain

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6
Q

3 major subdivisions of the brain

A

forebrain
midbrain
hindbrain

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7
Q

what makes up the outer forebrain

A

cerebrum
corpus striatum
hippocampus

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8
Q

what makes up inner forebrain

A

thalamus
hypothalamus

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9
Q

what makes up midbrain

A

substantia nigra

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10
Q

what makes up hindbrain

A

cerebellum
medulla oblongata
pons
reticular formation

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10
Q

what makes up hindbrain

A

cerebellum
medulla oblongata
pons
reticular formation

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11
Q

what does the outer forebrain comprise of

A

nerve cells
grey matter

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12
Q

what are the 4 lobes on the outer forebrain

A

frontal
temporal
parietal
occipital

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13
Q

what is the surface area of the brain increased by

A

ridges (gyri) and grooves (fissures and sulci)

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14
Q

name of the 2 sulci on outer forebrain

A

central sulcus
lateral sulcus

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15
Q

what is the outer forebrain concerned with

A

sensory and motor functions

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16
Q

what coordinates body movements

A

corpus straitum

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17
Q

2 things that the corpus straitum is part of

A

outer forebrain
basal ganglia

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18
Q

2 things that the hippocampus is part of

A

outer forebrain
limbic system

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19
Q

what part of the brain is involved in memory

A

hippocampus

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20
Q

what does the limbic system coordinate

21
Q

what is the thalamus responsible for

A

relay centre
recieves sensory input - cerebrum
relays cerebrum moter output to other areas

22
Q

what does the hypothalamus regulate

A

autonomic endocrine systems
essential for hunger, thirst, osmotic balance, body temp, metabolic rate

23
Q

what does the hypothalamus regulate

A

autonomic endocrine systems
essential for hunger, thirst, osmotic balance, body temp, metabolic rate

24
2 things that substantia nigra is part of
basal ganglia midbrain
25
what does the cerebellum control
fine, coordinated body movements
26
what does brain stem reticular formation modulate
wakefullness/sleep
27
what is pons/brain stem coordinate
visceral reflexes (breathing, digestion, HR)
28
ventral root
motor/efferent nerves leaving cord and innervate effectors
29
dorsal root
sensory/afferent nerves entering body
30
dorsal root ganglion
sensory nerve cell bodies
31
what is the spinal cord surrounded by
ascending and descending nerve tracts
32
what is in the centre of the spinal cord
neuronal cell bodies
32
what is in the centre of the spinal cord
neuronal cell bodies
33
3 things that make up blood brain barrier
plasma interstitial fluid cerebrospinal fluid
34
4 things the liquid of the BBB does
-supplies metabolites -physically protects the brain -provides appropriate chemical environment for neuronal function -removes waste
35
what does the BBB rely on
blood glucose and O2 no glycogen stores
36
structural specialisations that help the BBB separate CNS from blood
tight junctions between endothelial cells astrocytes as second barrier
37
what is allowed to pass from blood to CNS
-small non ionised, lipid soluble compounds eg O2, CO2. hormones -substrates for specific transporters eg glucose, ess aa, ions
38
what is not allowed to pass from blood to CNS
proteins, substances bound to plasma proteins, toxins, pathogens, most drugs
39
what occurs to BBB and CNS when injury or inflammation occurs eg meningitis
BBB breakdown CNS exposed to harmful substances
40
what occurs to BBB and CNS when injury or inflammation occurs eg meningitis
BBB breakdown CNS exposed to harmful substances
41
what fills ventricular spaces in brain
CSF
42
what is also filled with CSF in brain
2x lateral 3rd 4th spinal cord
43
2 things that CSF does to help the brain
-cushions brain and spinal cord from physical forces -aids removal of waste to venous system
44
how does CSF exit
via one way valves to veins
45
what produces CSF
choroid plexus
46
what type of cells line ventricles
ependymal cells
47
2 things the choroid plexus is composed of
ependymal cells capillary bed
48
how is water driven into ventricle
ependymal cells actively secrete Na into ventricle and Cl follows