Blood Flashcards
(26 cards)
blood consists of
formed elements and plasma
plasma is
55%
formed elements
45%
plasma composed of
92% water, 6% proteins ( albumin, globulins, transferrin and fibrinogen) and ions, nutrients, gases, waste
formed elements
majority RBC, then WBC, and platlets
major contributor to colloid pressure of plasma
albumin
fibrinogen function
form fibre threads to blood clot
where are plasma proteins produced
liver
what is spectrin
cytoskeleton protein that binds to cytosolic side of membrane protein t, responsible for elastic strength in RBC
maturation of RBC takes
4 days
all blood cells are derived from
hematopoietic stem cells (hemocytoblasts)
stages of RBC
hemocytoblast –> basophilic erythroblasts, polychromatic erythroblasts, then lose nun to become reticulocytes
what creates platlets
fragments of egakaryocytes
leukopenia
reduction of WBC
reduction of RBC
aplastic anemia
destruction of RBC
in spleen and liver –> phagocytosis
PCV
% of RBC
normal democrat
45% men, 42% women
polycythemia
high PCV
neutrophils
phagocytic cells
migrate out of BV and enter tissue
eosinophils
protect against parasites, and allergies, release anti-inflammatory substances
basophils
histamine and heparin release
hemostasis
stoppage of blood flow
- platelets release platelet factors, attract more and clog wound
blood clotting mechanism
- release clotting factors
- formation of thrombin by prothrombin factor and calcium acting on prothrombin
- thrombin forming fibrin from fibrinogen
