bone tumours Flashcards

(45 cards)

1
Q

osteosarcoma spread from

A

lung

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2
Q

chondrosarcoma spread from

A

prostate

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3
Q

ewings sarcoma spread from

A

kidneys and thyroid

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4
Q

multiple myeloma spread from

A

breast

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5
Q

risk factors for bone cancer

A

radiotherapy, pagets, fibrous dysplasia, multiple enchondromas, p53 RBI

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6
Q

presentation of bone cancer

A

usually not associated with movement, worse at night, swelling and erythema over joint, palpable mass, pathological fracture

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7
Q

diagnosis of bone cancer

A

radiographs, CT, MRI, bone scan

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8
Q

treatement of bone cancer

A

chemo, radiotherapy, hormone, surgery - both

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9
Q

what is the most common sarcoma of bone

A

osteosarcoma

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10
Q

who is osteosarcoma common in

A

children and young adults - 2nd peak in elderly

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11
Q

where does osteosarcoma present

A

usually distal femur or proximal tibia

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12
Q

what do 10-20% of osteosarcomas present with

A

pulmonary mets

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13
Q

treatmemt of osteosarcoma

A

chemotherapy and limb salvage

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14
Q

who does ewings sarcoma present in

A

people 5-25 years of age

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15
Q

where is ewings sarcoma usually found

A

diaphysis of long bones - again distal feur / pox tibia

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16
Q

treatments of ewings sarcoma

A

chemotherpy with limb salvage +/- adjuvant radiation

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17
Q

what is a chondrosarcoma

A

malignancy of chondrocytes

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18
Q

who presents with chondrosarcomas

A

40-75 year olds

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19
Q

where do chondrosarcomas tend to present

A

pelvis, proximal and distal femur

20
Q

what does a osteeoid osteoma look like on x ray

21
Q

what is a osteoid osteoma

A

painful benign tumour of long bones

22
Q

who gets osteoid osteomas

A

5-25 year olds

23
Q

presentation of osteoid ostemoma

A

pain worse at night - releived by aspirin

24
Q

treatment of osteoid osteoma

A

resolves spontaneously - can treat with radiofrequency ablation

25
what is the most common benign bone tumour
osteochondroma
26
what is an osteochondroma
benign lesion formed from abnormal cartilage
27
what can osteochondromas be
hereditary - multiple
28
who gets osteochondromas
adolescents and young adults - can be caused by trauma
29
what is a enchondroma
a benign intramedullary cartilage lesion
30
who gets enchondromas
20-50 year olds
31
presentation of enchondromas
incidental finding
32
what is the treatment of enchondroma
conservative - curettage and bone grafting if asymptomatic
33
when do bone tumours become visible on x rays
when >50% of cortex is destroyed
34
1 year old with bone lesion
neuroblastoma
35
1-10 year old with bone lesion
ewings sarcoma
36
10-30 year olf with bone lesion
osteosarcoma or ewings
37
30-40 year old with bone lesion
fibrosarcoma, osteosarcoma, lymphoma
38
40 + with bone lesion
metastatic carcinoma or multiple myelona
39
red flags for bone tumours
pain - increasing, persistant, worse at night, not traumatic
40
synovitis
inflammation of joint and tendon sheath lining
41
enthesitis
inflammation at sites where ligaments and tendons attach to bone
42
seronegative arthritides
ankylosing sponylitis, psoriatic arthritis, reiters syndrome
43
distinctive ditribution of psoriatic arthritis
small joint sof hands and feet - DIP joints, IP joint great toe
44
ankylosing sponylitis distinctive distribution
scattered large lower limb joints
45
reiters syndrome distinctive distribution
scattered large lower limb joints and lower limb entheses