Bones (Development)

Question 1

Define osteogenesis

Answer 1

The development of bone from a small cartilage model, to an adult bone

Question 2

What are the two ways that bones can form

Answer 2

• Endochondral ossification
• Intermembranous ossification

Question 3

Where does intermembranous ossification occur

Answer 3

Within a connective tissue membrane

Question 4

Which of the two forms of ossification do flat bones come from

Answer 4

Intermembranous ossification

Question 5

What three steps do flat bones have to go through to become a full bone

Answer 5

• Begin with a group of cells differentiated into osteoblasts
• clustered into ossification centers
• Secrete matrix material and collagenous fibrils in all directions

Question 6

T/F: Little amounts of ground substance need to be accumulated around each osteoblast in intermembranous ossification

Answer 6

False; Large amounts of ground substance need to be present

Question 7

What two things create the bone matrix in intermembranous ossification centers

Answer 7

Ground substance with collagenous fibers embedded in it

Question 8

When does the bone matrix calcify in intermembranous ossification centers

Answer 8

When calcium salts are deposited

Question 9

What forms spongey bone in intermembranous ossification centers

Answer 9

Trabeculae

Question 10

Define appositional growth

Answer 10

When osseous tissues are added to the outer surface of spongey bone in an intermembranous ossification center

Question 11

Define interstitial growth

Answer 11

When a bone grows from the center to the ends of the bone

Question 12

When does the collar bones become produced

Answer 12

When the periosteum develops