C-10 Flashcards

(33 cards)

1
Q

what would you find in the epidermis

A

outermost: oil and salt
granulosum: waterproof keratinized skin
spinosum: dendritic cells and karatinocytes
basale: basal cells and melanocytes

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2
Q

what would you find in the dermis

A

blood vessels
nerve endings
sebaceous glands
hair follicles

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3
Q

what is the tonicity of the skin

A

hypertonic

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4
Q

components of the normal skin flora

A

viruses
yeast
gm+ bacteria

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5
Q

virulence

A

virulence factors help microbes evade the immune system

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6
Q

how would you experimentally determine whether something is a virulence factor

A
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7
Q

pimple

A

when the base of a hair follicle
becomes red, swollen, and filled with pus

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8
Q

stye

A

(staph and eye) AKA hordeolum – when
folliculitis occurs in an eyelash follicle at the base of the eyelid

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9
Q

furuncle

A

(boil) is a larger, more painful
folliculitis that comes from the spread of the infection into surrounding tissues

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10
Q

carbuncle

A

is when several furuncles
coalesce, usually in areas of thicker skin (like the back of the neck). Systemic, deeper infectin – triggers fever and chills

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11
Q

reliable way to spot measles

A

kopek’s spots on oral mucosa

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12
Q

caused by herpes

A

cold sores
genital herpes
chicken pox
shingles

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13
Q

MMR vaccine

A

measles
mumps
rubella
- live attenuated and combination vaccine

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14
Q

papillomaviruses causes

A

warts

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15
Q

good candidate for shingles vaccine

A

60+ that had chicken pox as a child

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16
Q

disease caused my fungus

17
Q

fungi that cause dermatomycosis

A

dermatophytes

18
Q

ringworm

19
Q

2 fungi in skin

A

Candida albicans and malassezia

20
Q

cutaneous mycoses

A

direct or indirect contact; or when antibiotics kill normal bacterial flora and allow inhabitants to overgrow

21
Q

s. aureus

A

nose
makes coagulase and other enzymes

22
Q

s. epidermidis

23
Q

disease caused by s. aureus

A

impetigo
scalded skin syndrome
folliculitis
MRSA

24
Q

disease caused by s. pyogenes

A

strep throat
necrotizing facsiitis
impetigo
erysipelas

25
pseudomonas aeruglnosa makes a green pigment called
pyocyanin; damages host cells with reactive oxygen species
26
gas gangrene
clostridium perfringens (gm+) clean wound, debride, aggressive IV antibiotics
27
most bacteria found in
epidermis along with dendritic cells and dead cells
28
hair follicles and sebaceous glands found in
dermis
29
necrotizing diseases
necrotizing fasciitis gas gangrene
30
s. aureus
treated with semisynthetic derivative
31
anti-phagocytic virulence factors
capsule slime layer A and M protein
32
virulence factors that help bacteria invade deeper into the skin
enzymes and toxins
33
factors that make pseudomonas aeruginosa a problem when treating burn patients
- lots of virulence factors - ubiquitous - grow in antiseptics and disinfectants - thrive in warm and moist environments