C. Diff Flashcards
1
Q
True or false: Metronidazole should not be co-administered with vancomycin in any case of C. diff
A
False. Combined for fulminant C. diff episodes
2
Q
Which vancomycin dosing strategy is associated with the lowest recurrence rates?
A
Taper + pulse dosing
3
Q
What is bezlotoxumab?
A
Fully human IgG1 monoclonal antibody that binds to C. diff toxin B and prevents its effects on epithelial cells
4
Q
Rifaximin chaser protocol
A
After initial CDI treatment, rifaximin 400mg BID x 14 days
5
Q
Place in therapy of fecal transplant or ser-109 administration
A
Replace normal flora to restore balance. Ser-109 has much more organisms and more competitive organisms than a regular probiotic
