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Endocrine (updated 2016) > Calcium > Flashcards

Flashcards in Calcium Deck (31):
1

What form of calcium is in your bone

Ca:PO4 complex

2

What happens when calcium passes through glomerular filtrate

98% is passively reabsorbed

3

What are the major regulatory sites of calcium

Bone, kidney, small intestine

4

Where is half of your calcium in your blood

Protein bound

5

How do you calculate K

Ca x PO4

6

what is the normal range for K

30-50

7

What happens when K is > 60-70

Ca salts are deposited as Ca:PO4 complex

8

What happens when K is below 30

bone reaborption

9

What is the hormonal control of calcium

Parathyroid gland secreting PTH

10

Is PTH the same throughout species

Yes

11

What does PTH do to bone

Increases bone resorption

12

What does PTH do to the kidney

Stimulates activation of Vit D
Increases tubular calcium reabsorption
decreases tubular phosphate reabsorption

13

What does PTH do to the intestine

Calcitrol increases intestinal absorption of calcium

14

What does Calcitonin do

Opposite of PTH
Decrease levels of Ca in blood by inhibiting bone reabsorption
Decreases tubular calcium reabsorption

15

How is Vitamin D different than other vitamins

made in one place and acting at others
meets criteria for hormone

16

What are the steps to make vitamin D

sun or diet- makes vitamin D3> liver-25(OH) vitamin D > kidney (using PTH) 1,25(OH)2 vitamin D

17

What is the major action of VItamin D in the gut

Stimulate transepitheial transport of Ca and phosphate in the small intestine

18

What are the 3 principle tissues that regulate Ca

intestines
kidney
bone

19

What happens in Milk Fever

Hypocalcemic disorder associated with initiation of lactation in dairy cows. Low Ca and PO4

20

Where is hypoparathyroidism most comon

young dogs/cat 1-4 years old

21

How does hypoparathyroidism occur

autoimmune, surgery for hyperthyroidisim

22

Where is hyperparathyroidism occur

common in dogs

23

What happens in hyperparathyroidism

High PTH
High Ca
Low PO4
Bone loss

24

How do you treat hyperparathyroidsim

Surgery

25

What happens in secondary hyperparathyroidism

Diet induced
Low Ca
Low PTH
Bone loss

26

What happens during Hypervitaminosis

Suppressed PTH
High Ca and PO4
Bone breakdown
used in rodenticides

27

How to differentiate between 1, 2 hyperparathyroidism, and hypervitaminosis D

1: Increase in serum calcium. High PTH
2: Low serum calcium. High PTH
Hyp D: High serum Ca. Low PTH

28

What happens in hypercalcemia of malignancy

Hypercalcemia
Low PTH

29

What happens in primary hyperparathyroidism

Hypercalcemia
High PTH

30

What happens in hypervitaminois D do

Hypercalcemia
low PTH

31

How do you get calcium in

Intestinal absorption, bone resorption