Cancer, GI, and Toxicology Drugs Flashcards Preview

Pharmacology > Cancer, GI, and Toxicology Drugs > Flashcards

Flashcards in Cancer, GI, and Toxicology Drugs Deck (36):
1

What are the rescue drugs for the following anti-Cancer drugs?
> Methotrexate
> Cyclophosphamide
> Doxorubicin
> Cisplatin

> Methotrexate --> Leucovorin
> Cyclophosphamide --> Mesna
> Doxorubicin --> Dexrazoxane
> Cisplatin --> Amifostine

2

What is are the commonly used drugs for:
Acute Lymphocytic Leukemia in children

Prednisone, Vincristine, and Asparaginase or an Anthracycline plus intrathecal Methotrexate

3

What is are the commonly used drugs for:
AML in adults

Cytarabine and Idarubicin or Daunorubicin

4

What is are the commonly used drugs for:
Breast Carcinoma

Cytotoxic agents, hormonal therapy with Tamoxifen or an Aromatatse inhibitor (anostrozole), TRASTUZUMAB

5

What is are the commonly used drugs for:
CML

Imatinib newer tyrosine kinase inhibitors, interferon

6

What is are the commonly used drugs for:
Colon Carcinoma

Fluorouracil plus Leucovorin plus Oxaliplatin

7

What is are the commonly used drugs for:
Hodgkin's Lymphoma

ABVD regimen: doxorubicin (Adriamycin), Bleomycin, Vincristine, Dacarbazine, and Prednisone

8

What is are the commonly used drugs for:
NHL

CHOP regimen: Cyclophosphamide, Doxorubicin, Vincristine, and Prednisone) plus Rituximab

9

What is are the commonly used drugs for:
Ovarian Carcinoma

Paclitaxel and Carboplatin

10

What is are the commonly used drugs for:
Pancreatic Carcinoma

Gemcitabine and Erlotinib

11

What is are the commonly used drugs for:
Prostate Carcinoma

GnRH agonist (Leuprolide) or antagonist (Abarelix) and androgen receptor antagonist (Flutamide)

12

What is are the commonly used drugs for:
Lung Ca

Carboplatin, Paclitaxel, and Bevacizumab

13

What is are the commonly used drugs for:
Testicular Carcinoma

PEB regimen: Cisplatin (Platinol), Etoposide, and Bleomycin

14

Activated Charcoal is EFFECTIVE for:

Amitryptiline / Barbiturates
Carbamazepine / Digitalis Glycosides
Phencyclidine / Propoxyphene
Theophyline . TCA
Valproic acid

15

Activated Charcoal is NOT effective for:

Iron / Lithium / Potassium / Alcohols / Cyanide / Corrosive / Acids / Solvents

16

Utility of Hemodialysis EFFECTIVE for:

Carbamazepine / Ethylene glycol / Lithium / Methanol / Metformin / Phenobarbital / Salicylate / Theophylline / Valproic acid

17

Utility of Hemodialysis NOT effective for:

Amphetamines / Antidepressants / Antipsychotic drugs / Benzodiazepines / Calcium channel blockers / Digoxin / Metoprolol / Propranolol / Opioids

18

What is the antidote for Acetaminophen?

Acetylcysteine

19

What is the antidote for Cholinesterase inhibitors?

Atropine

20

What is the antidote for Quinidine, TCAs?

Bicarbonate

21

What is the antidote for Fluoride, CCBs?

Calcium

22

What is the antidote for Iron?

Deferoxamine

23

What is the antidote for Digoxin?

Digoxin antibodies (Digibind)

24

What is the antidote for Caffeine, theophylline, sympathomimetics?

Esmolol

25

What is the antidote for Methanol, ethylene glycol?

Ethanol

26

What is the antidote for Benzodiazepines, zolpidem?

Flumazenil

27

What is the antidote for Methanol, ethylene glycol?

Fomepizole

28

What is the antidote for Beta adrenoceptor blockers?

Glucagon

29

What is the antidote for Hypoglycemics?

Glucose

30

What is the antidote for Cyanide?

Hydroxocobalamin

31

What is the antidote for Opioid analgesics?

Naloxone

32

What is the antidote for Carbon monoxide?

Oxygen

33

What is the antidote for Muscarinic receptor blockers?

Physostigmine

34

What is the antidote for Organophosphates?

Pralidoxime

35

What is the antidote for Heparin?

Protamine sulfate

36

What is the antidote for Warfarin?

Vitamin K, FFP