Flashcards in Endocrine Drugs Deck (19):
Differentiate Wolf-Chaikoff effect from Job-Basedow phenomenon.
Wolf-Chaikoff effect: ingestion of iodine causes hypothyroidism
Job-Basedow phenomenon: ingestion if iodine causes hyperthyroidism
Which antithyroid drug inhibit peripheral conversion to T4 to T3?
What drug can cause drug-induced hyperthroidism?
Addison VS Conn
Addison's = Adrenal insufficiency
Conn's = adrenal exCess
NORgestimate, NORerthindrone and NORgestrel are NOT ESTROGENS. They are PROGESTINS!
TAnggal Mammary Mo = TAMOxifen
Clone Me Phlease = Clomiphene
Flutamide = Fake Androgen
FinAsteRIde = Five Alpha Reductase Inhibitor
LISpro = mabiLIS
gLARGine = Go Large!
LANTus = LANTa na sa sobrang tagal!
Why is there paradoxical improvement of diabetes in patients with end-stage renal disease?
insulin has prolonged half life due to decreased clearance
Which patients are more prone to developing hypoglycemia with insulin use?
advanced renal disease
children younger than 7 years
Why are the only routes of administration for insulin subcutaneous and IV?
TRANSDERMAL --> does not result in a reproducible and sufficient transfer of insulin across the skin
ORAL --> lack of a specific peptide carrier system in the gut
INTRANASAL --> bioavailability was low ang metabolic effect lasted too short to be of clinical usefulness
INTRAMASCULAR --> overall metabolic response not comparable to SC
INHALATION --> most promising; comparable to SC and IV but is still presently in Phase III trials (Exubera)
PIOGlitazone = pampa-POGI ng INSULIN para di mo na ma-resist
Are BANGKOK PILLS safe for weight loss?
ephedrine, fenfluramine, phentermine
adverse effect: valvular heart disease
Describe the function of Osteoblasts and Osteoclasts.
osteoBlast = Builds Bone
osteoclasts = CLeaves / resorbs Bone
ParaThyroid Hormone (PTH)
What are the signs and symptoms of Excess PTH?