Carbohydrates META Flashcards

1
Q

The enzyme in the mouth is called

A

Alpha Amylase or ptyalin

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2
Q

Alpha amylase requires ____ ion for activation under ___pH

A

Chlorine
6.7

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3
Q

Amylopsine is found where

A

Duodenum

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4
Q

All carbohydrates absorbed by the body are _____

A

Monosaccharide

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5
Q

SGlut 1 and SGlut 2 are located at ___&___

A

Intestines
Kidney

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6
Q

Glut4 are mainly located at

A

Skeletal muscle and adipose tissue

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7
Q

Glucose and galactose are absorbed by_____ transporter

A

SGlut

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8
Q

Phase 2 of glycolysis is called____

A

Preparatory stage
Where glucose is converted to glyceraldehyde-3-phosphate

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9
Q

Glucose is freely permeable at_____

A

Liver cells

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10
Q

Glucose is actively transported at _____

A

Intestinal mucosa and kidney

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11
Q

Insulin aids absorption at ______

A

Cardiac, skeletal, diaphragm and adipose tissues

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12
Q

Bromohydrozyacetone inhibits _____ part of glycolysis and why?

A

Stage 5
It resembles dihydroxy acetone phosphate so it binds with phosphotriose isomerase

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13
Q

How much energy is used up at phase one of glycolysis

A

2

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14
Q

Gluconeogenesis occur in ___ and ____
Majorly___

A

Liver and kidney
Liver 90%

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15
Q

During starvation does the kidney become a major site of gluconeogenesis?

A

Yes

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16
Q

Pyruvate carboxylase is found in the mitochondria of ___ & _____ by not ______

A

Kidney & liver
Muscle

17
Q

What inhibits gluconeogenesis (at fructose 1’6 bisphosphate)?
And what fovours it?

A

High level AMP
High level ATP and Low AMP

18
Q

During gluconeogenesis how many ATP is required to form 1 glucose

A

6 ATP

19
Q

In Sucrose, the glucose is taken up ny____ anD fructose by ____

A

SGLUT1
GLUT1

20
Q

Liver uses_____ And Muscle _____ transporter?

A

GLUT 2
GLUT 4

21
Q

_____ hydrolyzes limit dextrin into ___&_____

A

Isomaltase(1-6 glycocydic bond)
Maltose and glucose

22
Q

Drugs such as ___& ____ inhubits Na pump and also inhibit active transport of sugar
____ inhibits metabolic energy and also inhibits active transport of sugar?

A

Strophanthin
Dinitrophenol

23
Q

____ glycoside inhibits glucose transport by displacing Na from its binding site?

A

Phloridin

24
Q

Deficiency in what vitamin diminishes glucose absorption

A

Vitamin B, thiamine(B1) , pyrodoxine(B6) , pantothenic acid(B5)

25
Q

What’s Rapport Leubering cycle

A

In the erythrocytes, step 7 (conversion of 1,3-BPG to 3-PG) of glycolysis is bypassed.
Bisphosphoglycerate mutase converts 1,3-bisphosphoglycerate (BPG) to 2,3-BPG. Then BPGphosphatase removes the phosphate group to form 3-phosphoglycerate

26
Q

Why can’t ketogenic compounds like acetyl coA give rise to synthesis of glucose?

A

Irreversible nature of pyruvate hydrogenase

27
Q

Fructose intolerance can be due to?
Fructose can still be phosphorylated by fructose kinase bt energy will be lacking Becuz ph is need to form ATP from ADP

A

Aldolase B– liver failure

28
Q

____ causes fructosemia?

A

Lack of fructose kinase

29
Q

Fructose induced hypoglycemia is caused by?

A

Fructose 1-6 bisphosphate

30
Q

Absent if ____ is the most common cause of galactosemia

A

Uridyl tranferase

31
Q

Glycogenesis involves ___ phases

A

Synthetic phase and catabolic phase

32
Q

A debranching enzyme called

A

Oligo α-(1,4)-glucantransferase which contains two
activities, glucantransferase and glucosidase, removes the terminal 3 glucose residues of one
branch and attaches them to a free C4 end of a second branch