Vitamins Flashcards

(45 cards)

1
Q

Vitamin D can be formed by _____ and naicine from_____ by the body

A

Cholesterol
Tryptophan

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2
Q

Vitamins can be classified into

A

Water soluble and fat soluble

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3
Q

Water soluble fats includ

A

Vitamin
B1( thiamine)
B2 ( Ribuffaxin)
Naicine ( nicotinic acid)
B5 (Pantothenic acid)
B6 (pyrodoxine)
Biotin
Vit. B12 (Cobalamin)
Folic acid
And C (accorbic Acid)

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4
Q

When phosphorus is added to thaimine it’s converted?
It’s function

A

Thaimine Pyro phosphate which is a coenzyme for decarboxylation of keto acids

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5
Q

What are the enzymes that use TPP

A

Pyruvate decarboxylase
Pyruvate dehydrogenase
Branched chain alpha keto acid dehydrogenase
Alpha keto glutamate dehydrogenase
Transketolase

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6
Q

What are the sources of thaimine
Minimum requirements

A

Seeds, nuts, wheat, legumenious plants, lean meat
Adult–1. 0mg,
Infant& children–0. 4-1.3mg

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7
Q

Required intake increase in cases such as

A

Anoxia- shock, hemorrhage, hyperthyroidism, injury, illness, fever, pregnancy, lactation, increased carbohydrates intake

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8
Q

Deficiency in thiamine causes

A

Dry Beri beri & wet beri beri
Due to low plasma albumin and congestive cardiac failure

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9
Q

Symptoms of thiamine deficiency

A

Exhaustion, neuropathy, anorexia, cardiac disorders
Wenicke korsakoff syndrome found in alcoholic associated with thiamine deficiency

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10
Q

_____ is the component of the coenzyme FAD and FMN

A

Riboflavin, vit.B2

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11
Q

Riboflavin has ____ ring system binked by_____, which allows riboflavin to exist as____ and accept electrons either as pair or single

A

Isoalloxazine
Linked by ribitol
Exist as semiquinone

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12
Q

____ and ____ can only accept electrons as pairs?

A

NAD & NADP

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13
Q

FMN and FAD is ____ dependent

A

Atp dependent

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14
Q

Riboflavin is mainly used in?

A

Energy metabolism of lipid and sugar

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15
Q

Sources of riboflavin

A

Meat, nut, legumes, milk, fish, egg

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16
Q

Normal riboflavin in adults, infants and children

A

Adults–1. 5-2.5
Infants–0. 6
Children–1-1. 8

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17
Q

Lack of riboflavin is non-fatal

A
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18
Q

Y Is nicotinic acid not really considered a vitamin

A

Bcuz it can be formed by tryptophan but it’s inefficient
60mg for 1

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19
Q

Nicotinic acid contains a ___ ring

20
Q

Sources of nicotinic acid

A

Milk, lean meat, unrefined grain, cereals, tryptophan

21
Q

Required nicotinic acid

A

For adults– 17-21
Infant–6mg

22
Q

Deficiency in nicotinic acid causes

A

Pellagra
Diseases involving GIT & CNS

23
Q

Deficiency of Pyrodoxal phosphate causes

A

Hypo chronic microcytic anemia
In infant causes convulsiin due to inactive glutamate decarboxylase

24
Q

Bitulin is a coenzyme associated with

A

Carboxylation rxn

25
Sources of bitulin
Intestinal bacteria, liver, egg, peanut, milk
26
What can cause deficiency in bitulin
Excess consumption of white part of egg
27
Cabalanin(B__) has ____ ring
B12 tetrapyridine ring
28
B12 deficiency causes
Lack of intrinsic factors Pernicious anemia
29
Active form of folic acid is
Tetra hydro folate THF
30
Folic acid deficiency results in
Megaloblastic anemia, impaired absorption, neural tube defects
31
Burning foot syndrome is due to deficiency in?
Pantothenic acid B5
32
What vitamin forms an essential part of acetyl carrier moiety
Pantothenic acid B5
33
vit.C is also known as
Ascorbic acid
34
The H-bond in vit.C are
Triple hellix
35
Deficiency in vit. C causes
Scurvy-- weakening of collagin fibres Failure to hydroxylate proline and lycine
36
Hydroxylation reactions requires
Vit. C
37
What vit. are fat soluble Which serves as coenzyme
A, D, E, K Only K Vit. D is more like a hormone
38
Vit. A are present in diet as
Retinol & beta carotene
39
Deficiency in vit. A causes
Night blindness
40
Vit. D deficiency results in
Obstructive jaundice, partial gastronomy, GOT disorders, Ricket
41
Deficiency of vit. E only in pregnancy & new born baby
Hemolytic anemia
42
Vitamin E occurs in diet as 8 closely related compounds called
Tocopherol
43
Vitamin K are of ___ types? Absorption of vitamin K&E is dependent on
3 types Menaquinone(K2) in animals Phylloquinone(K2) in plants Appropriate fat absorption
44
_____ acts as q coenzyme for fat soluble vitamin
Vitamin K
45
Hh