Cardiovascular Disease Flashcards

(43 cards)

1
Q

What are possible fates of a plaque?

A

1) narrowing of vessel
2) plaque ulceration
3) intraplaque hemorrhage
4) peripheral emboli
5) wall weakening

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2
Q

What proportion of deaths are CV related?

A

25%

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3
Q

What are risk factors of CV disease?

A

1) age, f/h
2) diabetes
3) dyslipidemia, HTN
4) BMI > 25
5) physical inactivity
6) Tobacco use

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4
Q

At 55yo, how much longer can a pt with optimal risk factor profile expect to live?

A

14 years

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5
Q

Who has higher risk for CV dz – men or women?

A

men

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6
Q

Target range for cholesterol

A

< 180 mg/dL

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7
Q

Target range for fasting glucose?

A

< 100 mg/dL

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8
Q

Target range for BMI

A

< 25

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9
Q

Target range for physical activity

A

> 150 min/wk

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10
Q

What is defined as 1 serving of whole grains?

A

16 g = 1 oz

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11
Q

How many servings of whole grain per day has been shown to reduce risk for CV dz?

A

2.5 servings/day

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12
Q

What are the recommended servings for whole grain?

A

women: 2-3
men: 4

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13
Q

What are examples of whole grains?

A

amaranth, barley, buckwheat, corn, oat, quinoa

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14
Q

What nutrients are found in whole grains?

A

fiber, folic acid, Mg, vit E

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15
Q

What are sources of omega-3 fatty acids?

A

1) flax
2) soy/tofu
3) fatty fish
4) walnuts

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16
Q

What are benefits of omega-3 fatty acids?

A
anti-clotting
anti-arrhythmic
anti-inflammatory
-TGs
-BP
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17
Q

What nutrients are found in flax seed?

A

Mg, K, minerals,

& soluble fiber

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18
Q

Benefits of soluble fiber

A

-lipids

+laxation

19
Q

What is the best source of alpha-linoleic acid?

A

flax seed (1 tsp = 600mg)

20
Q

How much vinegar should be added to high glycemic-index foods?

21
Q

Benefits of adding vinegar to high glycemic-index foods?

A

-post-prandial glucose by 25%
+satiety (2*)

superior nutrient-calorie ratio when added to cruciferous greens

22
Q

What are the recommendations for fish in pt without CVD?

A

fish 2 x/week

23
Q

What are the recommendations for fish in patient with CVD?

A

0.5 - 1.8 g/day

24
Q

What the recommendations for fish in patient with high TGs?

25
What fish are sources of EPA & DHA?
tuna, mackerel, herring, anchovies, sardines
26
Benefits of garlic, onions, & leeks?
- LDL, -TG, -TC, -BP | - thromboses, -free radicals
27
How much garlic is required to decrease FA synthesis by 10%?
0.5 - 1 clove/day
28
What compound is found in red wine?
resveratrol -- a polyphenol
29
What are the apparent benefits of resveratrol?
-LDL, -platelet activity, -thrombosis, -free radicals
30
What foods are sources of resveratrol?
red wine, grapes, peanuts
31
What is the recommendation for wine per day?
men: 1-2 glasses/day women: 3 x/wk
32
Disadvantages of the DASH diet?
- - < 22% of patients adherent | - - complicated
33
What is the recommended amount of sodium in the DASH diet?
1000 - 2300 mg/day
34
What the requirements of the dash diet?
1) 1000 - 2300 mg Na/day 2) -weight 3) -EtOH 4) +K
35
What is the recommended amount of cholesterol according to the National Cholesterol Education Panel Step 1 Diet?
< 300 mg/day
36
What are the 2 sources of cholesterol?
1) dietary | 2) liver
37
What are good sources of cholesterol?
mono- and poly-unsaturated fats
38
What are sources of mono-unsaturated fats?
nuts, avocados, whole grain wheat, olive oil, popcorn, eggs
39
What are sources of polyunsaturated fats?
soy, fish, peanuts, grains
40
What is an omega egg?
An egg with increased amount of omega-3 FAs.
41
What compound is found in chocolate?
flavanols
42
What are sources of flavanols?
Chocolate | Green & black teas
43
What are the benefits of flavanols?
1) -BP in HTN pts by +NO formation