Cardiovascular Pharmacology Flashcards by Jhaunte Braithwaite | Brainscape

Q

What are the categories of hypertensives?

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Q

What increases preload/afterload in the RAAS ?

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Q

What are the antihypertensives?

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Q

What are the angiotensin inhibitirs?

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What are the diuretics?

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What are the calcium channel blockers?

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Q

What are the B-adrenergic antagonists for antihypertensives?

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Q

What are the alpha antagonists?

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Q

What are the mixed a- and B- antagonists for antihypertensives?

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Q

What are the central a2 agonists of antihypertensives?

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Q

What are the direct vasodilators of antihypertensives?

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Q

What do ACE inhibitors do?

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Q

What are the effects of ARBs?

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Q

What are the MOA renin inhibitors?

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Q

What are the effects of thiazides?

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Q

What are the effects of loop diuretics?

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Q

What are the K-sparring diuretics?

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Q

What are the effects of calcium-channel blockers?

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Q

What are the adverse effects of B-blockers?

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Q

Adverse efffects: bradycardia; AV block, impotence, mask hypoglycemia, Dyslipidemia, exacerbate heart disease, exacerbate COPD, nightmares/sedation/ fatigue

A

B-blockers- atenolol/metoprolol/ propranolol/ labetalol/ pindolol

Propranolol- exacerbate COPD+ mask hyperglycemia

Labetalol/ pindolol doesn’t cause Dyslipidemia

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Q

What are alpha 1 blockers used for ? What are the adverse effects?

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Q

What are the adverse effects of alpha-2 agonists ?

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Q

What are the adverse effects of direct vasodilators?

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Q

What medications have theseadverse effects? Sedation, lethargy, xerostomia, impotence, rebound HTN, positive Coombs test, reversible lupus-like symptoms

A

Alpha-2 agonists

Clonidine- impotence, rebound HTN

Methyldopa- positive Coombs test, reversible lupus-like symp.

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Q

What meds cause these adverse effects? Reflex tachycardia, edema, drug induced lupus, hypertrichosis?

A

Direct vasodilators

Reflex tachycardia- give beta blocker

Edema- give diuretic

Hydralazine- causes drug induced lupus

Minoxidil- hypertrichosis

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Q

How can we treat hypertension in pregnancy ? What are the risks?

A

Q

What drugs are used in hypertension and diabetes?

A

Q

What drugs are used in Dyslipidemia?

A

Q

What drugs are given in hypertensive crisis?

A

Q

How does sodium nitroprusside affect afterload and preload?

A

Both Decrease

Q

What are the adverse effects of sodium nitroprusside?

A

Q

What’s the effects of fenoldopam?

A

Q

What is the general treatment rationale for angina?

A

Q

Contrast drugs that increase oxyfen supply and decrease oxygen demand

A

Q

Describe ranolazine effects & adverse effects

A

Q

What drugs are used in myocardial infarction?

A

Q

What drugs are used in systolic heart failure?

A

Q

What are the effects of digoxin?

A

Q

What are The adverse and risks of digoxin?

A

Q

A patient experiences adverse effects: vomitting, xanthopsia, hyperkalemia and arrythmias (decreased AV cond)

A

Digoxin

Q

What drugs are used in diastolic heart failure?

A

Q

What are the class 1A Antiarrhythmics?

A

Quinidine/Procainamide/Disopyramide

Q

What are the classIB Antiarrhythmics?

A

Lidocaine/mexiletine

Q

What are the class IC Antiarrhythmics?

A

Flecainide/propafenone

Q

What are the class II Antiarrhythmics?

A

B-blockers: propranolol/metoprolol/ esmolol/ carvedilol

Q

What are the class III Antiarrhythmics?

A

K+ channel blockers: Amiodarone/Sotalol/ Dofetilide/ibutilide

Q

What are the class IV Antiarrhythmics?

A

Ca+ channel blockers: Verapamil/diltiazem

Q

What Antiarrhythmics affect the SA node?

A

Q

What Antiarrhythmics impact the AV node?

A

Ca+ channel blocks., B-blockers. & digoxin

Q

How do class 1A Antiarrhythmics affect the action potential?

A

Q

Discuss the adverse effects of Class 1A Antiarrhythmics

A

Q

How do class IB impact the action potential?

A

Q

What are the adverse effects of class IB

A

Arrhythmias
Convulsions/coma

Q

What are the affects of Class IC on action potential?

A

Q

What are the adverse effects of class IC Antiarrhythmics?

A

Q

What is the impact of class 2 Antiarrhythmics in the action potential?

A

Q

What are the adverse effects of class III Antiarrhythmics ?

A

Q

How do class III Antiarrhythmics affect the action potential?

A

Q

How do class IV Antiarrhythmics affect action potential ?

A

Q

How does digoxin impact the heart? What is it used for?

A

Q

What are the uses of magnesium?

A

Q

What are the effects & uses & adverse effects of adenosine?

A

Q

What drugs have an effect on the CVS?

A