cardiovascular system drugs Flashcards

1
Q

B agonists:

A

isoproterenol* most potent
epi- use for COMPLETE av block
norepi
dopamine

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2
Q

phosphodiester inhibitors

A

aminophylline, caffeine

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3
Q

what is used in refractory cases & ionotropic effect on contractility and rate VIA camp

A

glucagon

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4
Q

what increases contractility

A

calcium salsts

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5
Q

what increases heart rate

A

atropine

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6
Q

what is a positive inotrope?

A

increases contractility

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7
Q

which inotrope is used in Congest Heart failure or atrial arrythmias

A

digitalis

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8
Q

what inoptrope at lose dose is used for tissue perfussion thats good for shock txt

A

dopamine

dobutamine has no perfussion

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9
Q

what vasodilators are used for Cong heart failure, hypertension and progressive renale failure

A
ACE inhibitors
captopril
enalopril *IV only, slower onset long duration
lisinopril
benazepril
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10
Q

what is used for arteriolar vasodilation

A

hydralizine

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11
Q

what is used for emergency vasodilation

A

nitrates

  • prazosin
  • na nitroprusside
  • nitroglycerin
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12
Q

what are the two inodilators?

A
  • phosphodiesterase inhibitors

- pimobendan (vetmedin)

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13
Q

what does pimobendan (vetmedin) do?

A

increase cardiac contractility and causes vasodil by inhibit PDEIII and sensitives troponin without actually increases inctracellular calcium

  • txt CHF dog, adjuct therapy in DCM, CVD
    safter than digitalsi
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14
Q

what b Blocker is used only in moderate/early heart failure + inhibn RAS and balanced vasodilator

A

carvedilol..blocks vasoconstriction..nonselective B/a1 blocker

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15
Q

what are class 1 tachyarrhythimas

A

sodium channel blockers (ventricular arrhythmias)

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16
Q

Class 1a sodium chan blockers

A

prolong
quinidine
procainamide
disopyramide

17
Q

class 1b sodium channel blockers

A

shorten
lidocain *DOC, procainamide is backup
phenytoin- dog only

18
Q

class 1c sodium channel blockers

A

flecainide- no effect

19
Q

what are class 2 tachyarrhythmias

A

b-blockers (ventricul and supraventric)

20
Q

what are examples of Class 2 tacchyarrythimias & what are they the DOC for?

A

propranol, timoloil, pindolol, atenolol, metoprolol

*DOC hyperthyroidism in cats

21
Q

what are class 3 tachyarrhythimas

A

agens that prolong action potenial duration (refraction arrhy)
-bretylium, amiodarone, sotalol

22
Q

what are class 4 tacchyarrht?

A

Ca channel blockers (supra and myocardia hypertrophy)

  • verapamil-
  • diltizem-DOC myco hyper cat
23
Q

what are examples of bradyarrhythmias

A

atropine-DOC for sinus brady and incomplete AV block
isoproterenol- sinus brady
epi- cardiac asystole-complete

24
Q

what are the vasoconstrictors

A

epi & norepi-nonselevctive a agonist
phenlyephinre- selective a1 agonist
epherdine and phenypropanolamine-direct and indirect sympathomimet..txt inctonenance

25
Q

non selective a blocker–txt of emergency hyperT

A

phentolamine and phenoxybenzamine

26
Q

selective a1 blocker

A

prazosin
terazosin
doxazosin

27
Q

presynaptic a2 agonist

A

clonidie

28
Q

nonselective b blocker

A

propanolol

29
Q

selective b blocker

A

atenolol

30
Q

b/a1 blocker nonselective

A

carvedilol

31
Q

indirect sympatholgtics

A

guanethide and bretylium

32
Q

what ACE inhibitor is best in renal failure patintq

A

benazepril

33
Q

what are the calcium channel blockers?

A

diphenylalkylamines (verapamil)
benzodiazepines (diltiazem)
dihydrophyridine(nifedipine and amlodipine(

34
Q

why would you use calcium channel blockers

A
  • antiarrhythimic
  • antihyperT
  • myocardia hypertropyh
  • antianginal
  • decrease perip resistance
  • decreae BPD