Brainscape's Knowledge GenomeTM


Top Flashcards (Certified)
All Flashcards

pharm 2 > shockry parasites > Flashcards

shockry parasites Flashcards

(60 cards)

Start Studying
1
Q

5 MOA’s of antiparasitic drugs

A
  1. inhibition of NM blockers
  2. inhibition of nueronal system
  3. inhibiton of energy metabolism
  4. damaage membrane integrity
  5. inhibition of reproduction
How well did you know this?
1
Not at all
2
3
4
5
Perfectly
2
Q

competitive NM blockers

A

piperazine

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
3
Q

Depolarizing NM blockers

A

levamisole

pyrantal

morantel

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
4
Q

cholinesterase inhibitors

A

dichlorvos

trichlorfon

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
5
Q

Activates G-protein couples R in LAT-1 and LAT-2 at NM junction increase release or inhibitory neuropeptides causing paralysis of somatic muscles and pharngeal pump resulting in death of parasite

A

emodepside..combo with praziquantail as spot on

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
6
Q

inhibition of Neuronal system- bind to GABA and/or glutamate-gated Cl channels which

  1. increase cl membrane causing flaciid paralysis of somathic muscles
  2. inhibits egg production of parasite
A

MACROCYTIC LACTONES

  • avermectins
  • milbemycins
How well did you know this?
1
Not at all
2
3
4
5
Perfectly
7
Q

inhibit enegy metabolism by:

  1. bind to tubulin of parasite disrupting cell division
  2. deplete glycogen reserves tue to inhibit fumurate reductase and block mitchondrial function- parasitic death
A

BENZIMIDAZOLES- albendazole

ANTITREMATODAS - clorsulon

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
8
Q

damage membrane integrity by:
1. release Ca+ from parasite muscle cell storage

  1. ionic changes
A

Praziquantel

Espsiprantel

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
9
Q

inhibit reproduction

A

Anitprotozoals- inhibit growth

benzimidazoles- ovicidal and larvicidal

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
10
Q

Anticoccidials (Eimeria & Isospora)

A
  1. amprolium
  2. decoquinate
  3. ionophore
  4. sulfonamides
How well did you know this?
1
Not at all
2
3
4
5
Perfectly
11
Q

anticoccidial

AMPROLIUM

A
  • inhibits thiamine transport
  • used to prevent coccidioses
  • approved in laying birds
How well did you know this?
1
Not at all
2
3
4
5
Perfectly
12
Q

anticoccidial

DECOQUINATE

A
  • inhibits mitochondrial electron transport
How well did you know this?
1
Not at all
2
3
4
5
Perfectly
13
Q

anticoccidial

IONOPHORE

A

monensin, lasalocid, salinomycin, narasin

  • prevent coccidioses
  • growth promoting feed-additive
How well did you know this?
1
Not at all
2
3
4
5
Perfectly
14
Q

anticoccidial

SULFONAMIDES

A
  • sulfadimethoxine, sulfaquinoxaline, sulfametazine*
  • *** ***treat outbreaks and prevention*
How well did you know this?
1
Not at all
2
3
4
5
Perfectly
15
Q

Giardiasis Drugs

A
  • metronidazole
  • benzimidazoles *NO bots
  • quinacrine
  • furazolidone
How well did you know this?
1
Not at all
2
3
4
5
Perfectly
16
Q

giardia

METRONIDAZOLE

A

DOC for anaerobes only (inhibit reductase/DNA synthesis)

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
17
Q

giardia

BENZIMADZOLES

A
  • albendazole– no GRUBS
  • fenbendazole

NO BOTS

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
18
Q

giadia

FURAZOLIDONE

A

use for PREGOS!

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
19
Q
A
  • metronidazole= DOG
  • furazolidone- pregos
How well did you know this?
1
Not at all
2
3
4
5
Perfectly
20
Q

Balantidiasis

A
  • Metronidazole
  • Tetracycline- inhibit 30S
How well did you know this?
1
Not at all
2
3
4
5
Perfectly
21
Q

Trichomoniasis

A
  • Metronidazole (dogs, horses)
  • ​Cliquinol (diarrhea in horses)
  • Carnidazole (pigeon canker
  • )
How well did you know this?
1
Not at all
2
3
4
5
Perfectly
22
Q

Toxoplasmosis

A
  • Clindamycin=DOC cat/dog
  • Sulfonamides
  • Potentiated sulfonamides
    • pyrimethamine
    • trimethoprim
How well did you know this?
1
Not at all
2
3
4
5
Perfectly
23
Q

histomonas meleagridis

A
  • Organic arsenicals
    • carbarsone, roxarsone, nitrarsone
How well did you know this?
1
Not at all
2
3
4
5
Perfectly
24
Q

Babesiosis in horses

A

Imidocarb

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
25
anaplasmosis ![Image result for anaplasmosis](https://encrypted-tbn0.gstatic.com/images?q=tbn:ANd9GcRHYzqzcbZd5X1XJixzYgawTvf_atmLV3ar4RJbSXLlflp0Hlpx)
oxytetracyline
26
Sarcocystis neurona (EPM)
* Nitrazoxanide * ponazuril * diclazuril * trimpethprim * pyrimethamine * vit E orally
27
anti-inflammatory
DMSO Flunixin glucocorticoids
28
cryptosporidiosis ![Image result for cryptosporidiosis parasite](https://encrypted-tbn1.gstatic.com/images?q=tbn:ANd9GcT69nSd7o362slYMJdRPzxaSWq-zbHxPfeHfwqgjv8bTMpjTQy7bg)
* paromomycin * azithromycin * nitazoxanide
29
Anti-trematodals ![Image result for trematode anatomy](https://encrypted-tbn1.gstatic.com/images?q=tbn:ANd9GcQ6e7zmFQnR40RDKHXtMxt7SVd_CshG8bp6XjD6QZCSPvXq4r-71Q)
* Clorsulon * liver fluke (F.hepatica) * Albendazole * liver fluke, cestorse and nematodes of GI and lungs in cattle \*THESE ACTS ONLY ON ADULTS, SO MUST REPEAT
30
Anti- cestodals ![Image result for cestodes](https://encrypted-tbn1.gstatic.com/images?q=tbn:ANd9GcTqgO9Dg3yjWQQPb0a_d806BLAJEYWb7UyFWMP-jGQJmSsyHG1A)
* Dichlorophene * Praziquantel * epsisprantel * fenbenazole
31
anit-cestode DICHLOROPHENE
DOG/CAT Taenia & Dipylidium
32
anti-cestode PRAZIQUANTEL ![](http://www.1800petmeds.com/images/products/420/10072_420.jpg)
DOGS-DOC Taenia pisiformis dip caninum, echinoccosus granulosis HORSES- also effective against Anoplocephala
33
anti-cestode ESIPRANTEL ![Image result for epsiprantel](https://encrypted-tbn3.gstatic.com/images?q=tbn:ANd9GcQOyu_ZuvzE0F-P3T3T8p0x36WFLqe4610cIwI_WzjcPecSwSUB)
DOG/CAT Taenia and Diplidium
34
anti-cestode FENBENDZOLE ![Image result for fenbendazole](https://encrypted-tbn1.gstatic.com/images?q=tbn:ANd9GcRmqeTj5ayE4A1NB7u734AC3Nb55sn9q6dbinqAIvF6i7NjbxQJ6A)
DOGS hooks, whips, taenia pisiformis **NO DIPYLIDIUM**
35
Avermectins
* Ivermectin- oral or injectible (cattle/swine) * Eprinomectin- pour on, apprived in beef & airy * Doramectin- IM or SQ cattle * Selamectin \*\*\*\* dog,cat, topical NO FLUKES horse, cattle, pig, SHEEP, dog/cat
36
AVERMECTINS: ivermectin, eprinomectin, doramectin Horses ![Image result for horses](https://encrypted-tbn2.gstatic.com/images?q=tbn:ANd9GcSNikebLJp-8yui3aE4ONG1vWiD61c4s-oovhK2FCNFZNFZNYlf)
Gi roundworms, lungworms and bots oral
37
Avermectins: Ivermectin, eprinomectin, doramectin Cattle ![Image result for cattle](https://encrypted-tbn2.gstatic.com/images?q=tbn:ANd9GcQ0jwnN-j90wCCAawSh3x0a0iC0sfAOHiQqXk7X8AIv6-1NXFEOkQ)
GI roundworms, lungworms, grubs, lice, mites/scabies
38
Avermectins ; ivermectin, eprinomectin, doramectin pigs ![Image result for pigs](https://encrypted-tbn1.gstatic.com/images?q=tbn:ANd9GcQlkK410HEFiTwVdYvCszAlceAbseUXB47BgayENnkzSbM8G0j3)
GI roundworms, lungworms, lice, mange mites
39
avermectins: ivermectin, eprinomectin, doramectin dog/cat
tissue stage of heartworm, PREVENT ONLY. NOT TREAT. elimiate larvae
40
Avermectin; vermectin, eprinomectin, doramectin SHEEP ![Image result for SHEEP](https://encrypted-tbn1.gstatic.com/images?q=tbn:ANd9GcRRWKCs2He-Lkrp4OkzZcl1GHC7G8R0IXhf1hnuYHEUXRJw-Emy)
GI roundworm, lungworms, and nasal bots\*
41
avermectin- SELAMECTIN ![Image result for SELAMECTIN](https://encrypted-tbn1.gstatic.com/images?q=tbn:ANd9GcQgrDnPo3GQeGTgBdIHr0XcnzF3U213SjDhX4-2NcDEG6GfDYxW)
*approved dog, cats \> 6 weeks, applied topically monthly* * kill adult fleas and prevent flea eggs from hatching * prevents heartworm * sarcoptic mange and ticks * intestinal hooks and rounds worms * ear mite
42
MILBEMYCINS
* milbemycin oxime * moxidectin
43
Miblemycin- Miblemycin oxime INTERCEPTOR
*approved in dogs \> 8 weeks* * *​​*prevent heart worm * prevent hook, round, whips
44
Milbemycin- Moxidectin
*pour on in cattle, oral in horses and dogs* * internal and external parasite control of cattle and horses * prevent heartworm in dogs-- ![Image result for advantage multi dogs](https://encrypted-tbn1.gstatic.com/images?q=tbn:ANd9GcRmH1ptUIMKAesbPLtBOisG8lJA4CS87CzUZmd59uZqk8-47zfHmA)
45
broad spectrum- BENZIMIDAZOLES
* albendazole- cattle * fenbendazole- dogs, horses, swine, \*LACTATING CATTLE * oxfendazole- horses, bef cattle * oxibendazole- horses and dogs
46
benzimidazoles- albendazole
approved in cattle, DO NOT USE IF PREGO * GI roundworms, lungworms, tapeworms, adult liver flukes
47
benzimidazoles- fenbendazole ![](http://i290.photobucket.com/albums/ll257/pjsanab/DSCN1555.jpg)
*approved in dogs, horses, swine, cattle AND LACTATING CATTLE\** * *​*dogs: ascarids, hooks, whips, tapes * horses: broad-spectrum * cattle: GI round, lung, moniezia benedini
48
benzimadazoles- oxfendazole ![Image result for oxfendazole](https://encrypted-tbn2.gstatic.com/images?q=tbn:ANd9GcTtzR6Vob_mbz0B7Cqm-v_cqbZNnI26ecZ5MqFMZfS43yKKrA7QXA)
*approved in horses and BEEF cattle* * adult moniezia bendini * ![Image result for cattle moniezia bendini]()
49
benzimidazole- oxibendazole ![Image result for oxibendazole](https://encrypted-tbn1.gstatic.com/images?q=tbn:ANd9GcSbHnzXBHEB9bWy4mqm7MTSQMrZJ0a19XeLyEZJVfKXl6ga9ADq)
approved in horses and dogs borad spectrum against GI roundworms
50
broad spectrum- IMIDATHIAZOLES
* febantel: horses, dogs,cats * Levamisole" cattle, sheep, swine \* narrow safety margin
51
Imidathiozoles- febantel
approved in horses, dogs, and cats * probenzimidazole * broad spectrum antinematodal actiity, wide safety margin
52
imidathiazoles- levamisole
approved in cattle, sheep and swne \* **narrow saftery margin** * acts against GI roundsworms and lungworms * administered orally , sq and topcailly
53
broad spectrum- TETRAHYDROPYRIMIDINES
* pyranitel: dog, horse, pigs * morantel: goats and cattle \* INCLUDING LACTATING CATTLE
54
tetrahydrophyrimidines- PYRANTEL
dog: large roundworms, hooks horses: pinworms, rounworms, stronglyes, and tapeworms @ large doses\*\* swine: large roundworms and nodular worms
55
tetrahydropyrimidines- MORANTEL
* cattle, including lactating dairy cattle * goats against GI nematodes
56
broad spectrum- ORGANOPHOSPHATES
* Dichlorvos: * swine: GI nematodes * dogs: rounds,hooks, whips * cats: rounds and hooks
57
narrow spectrum- anthelmintics
Piperazine: * approved in chd, turkeys, swine, horse, dogs and cats for txt of large roundworms horses: also strongles and pin worms swine: also nodular worms
58
HEARTWORM- ADULTCIDIAL THERAPY
**Melarsomine:** dogs IM, no cats!! ![Image result for melarsomine](https://encrypted-tbn2.gstatic.com/images?q=tbn:ANd9GcT6whrt99Pb_02Z_Lq9CnxaoSRsSNPHNfcxUPVNHLg3DlH0PsmeDw) * strict rest for 3-4 weeks
59
heartworm- MICROFILARICIDAL
* ivermectin = HEARTGUARD * milbemycin= INCTERCEPTOR ## Footnote * use 3-4 weeks after adulticidie therapy* * SE: circulatory collapse*
60
heart worm- PREVENTION
* ivermectin * milbemycin oxime * moxidectin * selamectin

pharm 2 (11 decks)

Brainscape helps you reach your goals faster, through stronger study habits.
© 2025 Bold Learning Solutions. Terms and Conditions