Cartilage

Question 1

Does cartilage have a blood supply ?

Answer 1

NO it is avascular

Question 2

Where is cartilage found /

Answer 2

areas of support and movement

Question 3

condrocytes

Answer 3

large rounded cells with LIGHT cytoplasm and small nuclei which produce matrix

Question 4

matrix

Answer 4

firm, high in glycosaminoglycans (GAG’s) and hyaluronic acid

Question 5

What are the three types of matrix

Answer 5

hyalin cartialge
elastic cartilage
fibrous cartilage

Question 6

What is the function of hyalin cartilage ?

Answer 6

it binds bones together, for joints because it has low friction

Question 7

synchondrosis

Answer 7

bondage of bones

Question 8

What type of fibers does hyalin cartilage have ?

Answer 8

type II collagen

Question 9

Can you stain cartilage with H ad E ?

Answer 9

no because i is in the form of fibrils and its refractive index is the same as the ground substance

Question 10

Cavities in the matrix of hyalin cartialge are called what

Answer 10

lacuane and they are for chondrocytes

Question 11

Where do chondrocytes originate from

Answer 11

mesenchymal cells

Question 12

Appearance of chondroblasts

Answer 12

basophilic cytoplasm, synthesize ECM do NOT aggregate in clusters

Question 13

where are chondroblasts found

Answer 13

growing cartilage

Question 14

chondrocytes

Answer 14

inactive cells have light cytoplasm

Question 15

isogenous groups

Answer 15

recently divided chondrocytes that are sitting in clusters in the lacuane surrouned by a territorial matrix and an interterritorial matrix

Question 16

Is the territiroial high or low in GAG’s

Answer 16

high

Question 17

is the interterritorial matrix high or low in GAGS

Answer 17

low

Question 18

what is perichondrium

Answer 18

collagenous membrane on the surface of cartilage that carries vessels and nerves (essential for the avascular cartilage

Question 19

What are the two layers of perichondrium

Answer 19

outer fibrous layer of dense connective tissue and an inner chondrogenic layer of mesenchymal cells

Question 20

When is perichondrium NOT present

Answer 20

when cartilage contacts with bone; articular surfaces

Question 21

Characteristics of Elastic Cartilage

Answer 21

elastic fibers in matrix
stains with resourcin-fuchsin or orcein
found in ears, cartilages of larynx
does NOT calcify with aging

Question 22

What are the characteristics of Fibrocartilage

Answer 22

combination of dense regular connective tissue and hyaline cartilage
chondrocytes are sitting in rows
large amt of collagen
no perichondrium

Question 23

Appositional growth

Answer 23

chondroblasts are formed by the inner layer of perichondrium (type 1 collagen) and they produce matrix (collagen type 2) and turn to chondrocytes

Question 24

interstitial growth

Answer 24

division of chondrocytes within the lacunae-isogenous groups