Cell- Cell Interactions

Question 1

what si CT

Answer 1

structural
hold cells body together
collagen nd elastin

Question 2

what is mesenchyme

Answer 2

body - mesodermal origin 
head neck - ectomesoderm origin 
loose 
unspecialised
gelatinous

Question 3

what is developed from mesenchyme

Answer 3

CT 
bone 
cartilage
Circulatory system
Lymphatic system

Question 4

what are 4 fundamental aspects of developmental biology

Answer 4

proliferation/growth size
pattern formation
morphogenesis shape
differentiation

Question 5

what is pattern formation

Answer 5

is the process by which cells develop embryo acquire identities that lead to a well ordered spatial pattern of cell activities

Question 6

what is sequentially

Answer 6

iminig of events

Question 7

what is reciprocal

Answer 7

one in control of other

Question 8

what is dynamic

Answer 8

happen quickly

Question 9

what are the two types of tissue intercation

Answer 9

instructive

permissive

Question 10

what is instructive tissue intercation

Answer 10

ability of one tissue to determine sp patterns of morphogenesis and diff that will develop in an assc tissue

Question 11

what is permissive tissue interactions

Answer 11

ability to provide certain conditions that is necessary for its committed partner tissue to progress to full expression of its pre determined phenotype

Question 12

what is a homotypic interaction

Answer 12

same time, place and species

Question 13

what is a heterotypic interaction

Answer 13

unrelated usually same time and sp

Question 14

what is a heterochronic intercation

Answer 14

same type and sp but diff time

Question 15

what is a heterosp interaction

Answer 15

similar areas but diff species

Question 16

what is organogenesis

Answer 16

secondary interactions

patterning right place

Question 17

what si organ rudiment

Answer 17

morphogenesis

proliferation

Question 18

what is organ sp structures

Answer 18

differentiation

Question 19

what are some experiments for cell cell interactions

Answer 19

early work tissue recombination 
organ culture filters
organ culture trowel dish 
bead implantation 
in situ hybridisation

Question 20

what is a tooth organ culture

Answer 20

100 yrs ago
hanging drop cultures
culture medium, chick plasma, embryo extract

Question 21

what is the nucelopore filter method

Answer 21

matrix biology other in vivo assays

Question 22

what si the trowel cultures method

Answer 22

lead to all sorts of possibilities in recomb

- homo/heterotypic, heterochronic, heterosp and mutants

Question 23

what happens in tooth development

Answer 23

simple form of organ culture

embryological classes

Question 24

what is mouse initiiatio embryological class

Answer 24

E9/10

Question 25

what si the bud, cap and bell embryological class

Answer 25

bud - E12 cap- E14 bell - E16

Question 26

what si the differentiation of cell types during tooth development like

Answer 26

``` cells more specialised amorphous blob dynamic reciprocal sequential ```

Question 27

what are cytokines and what happens during development

Answer 27

small mols move small dist receptors and signalling RNA sun of other cytokines and ECM mols

Question 28

what is BMP4

Answer 28

cytokine | E11 in dental lamina

Question 29

what is the heparin bead experiment =

Answer 29

induce MSX1 an MSX 2 and other transcription factors

Question 30

what is the extracellular matrix imp in

Answer 30

``` morphogenesis differentiation adhesion migration proliferation polarisation ```

Question 31

what does the ECM of the developing tooth contain

Answer 31

collagen IV fibronectin tenascin syndecan

Question 32

what are the stages of oral development

Answer 32

interaction between oral ectoderm and mesoderm