cell cycle and division (2) Flashcards
(43 cards)
non division phase
interphase (growth, preparation)
division phase
mitosis (division of nucleus), cytokinesis (division of cytoplasm, organelles)
when can a cell not go through division?
other cells inform the cell that more cells of that type are not required
not enough nutrients are available to provide for cell growth
DNA has not replicated
DNA is damaged
when are the 3 “checkpoints”?
G1 => S1 (is DNA intact)
G2 => M (has DNA been replicated)
metaphase => anaphase (are chromosomes aligned at centre)
chromatin
loose, stringy mass where chromosomes cannot be seen
chromosome
during mitosis, DNA coils and chromosomes can be seen
what are 2 types of chromosome appearances?
single stranded
double stranded
centromere
holds double stranded chromosomes together
chromatid
each strand in a double stranded chromosome
sister chromatids
two identical copies of a chromatid connected by a centromere
homologous chromosomes
2 identical pairs of chromotids
order of cell cycle events
interphase prophase metaphase anaphase telophase cytokinesis
what is the longest phase?
interphase
interphase
cells do ________
whatever activities it is meant to do and prepare for cell division
how does a cell prepare for division?
growing
making more organelles
replicating DNA
prophase
chromatin _______ and chromosomes become ______
condenses / visible
prophase
nuclear membrane starts to ______
break down
prophase
nucleolus ______
disappears
prophase
centrosomes move toward _________ and begin to form ______
opposite ends of cell / spindle fibres
metaphase
chromosomes line up ________
along centre of cell
metaphase
centrioles reach ________
opposite ends of cell
metaphase
each centromere attaches to ______
2 spindle fibres (one on each end)
metaphase
nuclear membrane is _____
completely dissolved
anaphase
daughter chromosomes are pulled to _________
opposite side of cell