Cell Cycle Control Flashcards Preview

CBIO3400 > Cell Cycle Control > Flashcards

Flashcards in Cell Cycle Control Deck (14):
1

draw CDK activity control diagram

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2

Cdc25 overexpression cells are:

small (shorter G2)

3

Cdc25+ activates this complex

Cdc2/Cdc13

4

wee1- mutants cells are:

small (short G2)

5

cells are larger when Wee1+ is overexpressed due to:

prolonged G2

6

activity of this is constant throughout cell cycle

CDK

7

Cdc13+/cyclin forms a complex with:

Cdc2/Cdk

8

protein Y-kinase that phosphorylates Cdc2/Cdk on Y15

Wee1

9

affect of Wee1 phosphorylation of Cdc2/Cdk

inhibition

10

protein phosphorylates T161 on Cdc2

CDK Activating Kinase

11

protein phosphatase removes phosphate group from Cdc2/Cdk

Cdc25

12

Cdc25 removes phosphate group from:

Y15

13

diagram CLN1 regulation of G1 cyclins

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14