Cell Function and Oncology Flashcards

1
Q

Why do cells adapt?

A

Respond to stress

Maintain homeostasis

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2
Q

5 main ways cells adapt

A
  1. Hypertrophy (more cell production for an organ or tissue)
  2. Atrophy
  3. Hyperplasia (more cell growth)
  4. Metaplasia (abnormal change in tissue)
  5. Dysplasia (different type of cell growth in an abnormal area)
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3
Q

trophy

A

Nourishment

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4
Q

plasia

A

growth

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5
Q

Where do all cells come from?

A

Stem cells

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6
Q

What is in the nucleus

A

DNA

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7
Q

Proliferation

A

Rapid reproduction

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8
Q

Mitosis

A

Type of reproduction of cells

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9
Q

Differentiation

A

Specialized cells

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10
Q

Gene expression

A

Brings out n appearance and function in a cell

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11
Q

What are daughter cells

A

identical

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12
Q

Apoptosis

A

falling off (cell death)

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13
Q

Phagocyte

A

What will consume a dead cell

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14
Q

Abnormal cell death

A

when the cell bursts

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15
Q

Necrotic tissue

A

Dead tissue

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16
Q

Gangrene

A

When bacteria and necrosis happen together.

No O2 so spreads easily (no blood flow)

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17
Q

Oncogenes

A

When a cell doesn’t die but has mutated DNA

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18
Q

Dysplasia

A

Cell mutates
May change in shape and structure
Still has special function
Still reversible

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19
Q

Premotor

A

Encourages a damaged or mutated cell to multiply

20
Q

Neoplasm

A

Not cancer

Cell growth that doesn’t respond to regulatory processes

21
Q

Anaplasia

A

Cell mutated and has lost special function

Hallmark of malignancy

22
Q

Tumor

A

Bunch of cells that don’t respond to normal functions

Can be benign or malignant

23
Q

How often does cell damage occur in the body

A

All the time

Most damage is handled

24
Q

Percentage of cancer in men and women

A

42% of women

45% men

25
4 most common cancers
Breast, prostate, colorectal, lung
26
Some risk factors
Genes, Radiation, oncoviruses, carcinogens, hormones, aging, immune system, and lifestyle (smoking, lack of exercise, poor diet, obesity)
27
Benign
Differentiated cells Does not metastasize (localized) Growth rate is slow Can cause damage through compression, obstruction, or distension
28
Malignant
Undifferentiated cells Does metastasize Growth rate is rapid Causes damage by destroying surrounding tissue
29
The tumor's ability to survive
O2 and nutrition
30
Angiogenesis
Growth of new blood cells | Tumor will secrete substances to get more blood vessels
31
2 ways to diagnose cancer
``` Tumor markers (blood tests) Histology and cytology (ex.biopsy) ```
32
3 ways a malignant cell can spread
Transcoelomic (penetrating a body cavity) Hematogenous (through blood) Lymphatic (through the lymphatic system)
33
Grading
Grade the degree of differentiation | **differentiated is good
34
Staging
Extent of the disease (1-4) 1. size of tumor 2. lymph node involvement 3. metastasize
35
Future of cancer treatment
testing target specific cells | personalized treatment because everyones cancer is different and each cell is different
36
Optimal goal for cancer treatment
Killing cancerous cells and preserving healthy ones
37
Surgical treatment for cancer
``` Removing the tumor Amputate Biopsy Prophylaxis Reconstruction ```
38
Radiation
Local tumor Destroys all cells in that area Must be immobile
39
Chemo
Not localized Affects every cell in your body Attacks fast multiplying cells
40
Prognosis
Likelihood of curing the disease
41
Remission
No physical signs of cancer cells
42
Relapse
Cancer returns after treatment in another part of the body
43
Cured
Remission for more than 5 years
44
2 objectives fro supporting a client
Minimize side effects | Promote a healthy lifestyle
45
Refractory
Not responding to treatment