Cell Pathology Case Studies Flashcards Preview

Y1 Fwong MCD Cell Path Mubarak > Cell Pathology Case Studies > Flashcards

Flashcards in Cell Pathology Case Studies Deck (17)
Loading flashcards...
1

Name the effects of helicobacter infection on the stomach?

Inflammation:
acute, chronic (including ulcers)

Cell damage:
atrophy, metaplasia, dysplasia

Neoplasia:
carcinoma, lymphoma

2

What is the key inflammatory cell of acute inflammation?

neutrophil polypmorph

3

Define an Ulcer

An open sore on an external or internal surface of the body, caused by a break in the skin or mucous membrane which fails to heal.

4

What is the key inflammatory cell of chronic inflammation?

lymphocyte

5

What is granumalatous inflammation?

Particular form of chronic inflammation showing granuloma formation

-Cluster of macrophages

-Involves specific immune reaction T cells

6

Name some causes for granumalatous inflammation?

Infection – TB, fungi, helicobacter

Foreign material

Reaction to tumours

Immune diseases (sarcoid, Crohn’s)

7

what is gastritis?

Gastritis is inflammation of the stomach lining and is usually termed acute or chronic gastritis

8

What makes a gastric ulcer an acute gastric ulcer?

Parenchymal cell regeneration and RESOLUTION

9

What makes a gastric ulcer a chronic gastric ulcer?

REPAIR by connective tissue and SCAR TISSUE FORMATION

10

Name the cellular adaptations seen in association with helicobacter gastritis?

atrophy
metaplasia and
dysplasia.

11

Define atrophy?

Shrinkage in the size of the cell (or organ) by the loss of cell substance

12

Define metaplasia?

A reversible change in which one adult cell type is replaced by another

13

Define Dysplasia?

Precancerous cells which show the genetic and cytological features or malignancy but not invading the underlying tissue

14

What is cancer grading based on?

based on the degree of histological differentiation

15

What is cancer stagin based on?

based on how far the tumour has spread

16

Name the main staging system for cancers and what the acronym stands for?

size and spread of the primary Tumour

Spread to regional Lymph Nodes

Presence of Metastases

TNM

17

Name 3 common sites of clinically important atheroma?

Coronary Arteries

Carotid arteries

Aorta or iliac arteries