Cell Physiology Flashcards

(36 cards)

0
Q

Powerhouse of the cell

A

Mitochondria

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1
Q

Contains DNA, Histones & Chromosomes, has nucleolus

A

Nucleus

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2
Q

Involve in detoxification, lipid synthesis, lipid soluble substances to water soluble substances

A

Agranular endoplasmic reticulum (SER)

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3
Q

For synthesis of proteins bound for

the cell membrane, lysosomes, outside of the cell

A

RER Ribosomes

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4
Q

For synthesis of proteins bound for the cytoplasm & mitochondria

A

Free floating ribosomes

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5
Q

For packaging, molecular tagging & synthesis of hyaluronic acid & chondroitin sulfate

A

Golgi apparatus

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6
Q

Contains proenzymes, neurotransmitters & replenishes cell membrane components

A

Secretory vesicles

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7
Q

For regression of tissues & autolysis; suicide bags of cells; destroys FB

A

Lysosomes

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8
Q

Degrades membrane-associated proteins; not membrane bound

A

Proteosomes

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9
Q

Contains oxidases, catalases, for detoxification

A

Peroxisomes

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10
Q

What do you call the specialized SER in skeletal muscle?

A

Sarcoplasmic reticulum

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11
Q

What do you call the specialized RER in the neuron?

A

Nissl substance

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12
Q

The only substance modified in the RET & not the Golgi apparatus

A

Collagen

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13
Q

What is added ti lysosome-bound proteins by the Golgi apparatus?

A

Mannose 6-phosphate

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14
Q

Lysosomes come from which organelle?

A

Golgi apparatus

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15
Q

Perixisomes come from which organelle?

16
Q

Wear & tear pigmenta that accumulates in lysosomes

17
Q

Disease with dynein missing in cilia & flagella

A

Kartagener syndrome

18
Q

What is the explanation for the situs inversus in Kartagener’s syndrome

A

Defective primary cilia

19
Q

What is the functional unit of the gap junction?

20
Q

What do you call the movement of substance through the apical & basolateral side?

A

Transcellular transport

21
Q

What do you call the movement of substances between cells through tight junctions?

A

Paracellular transport

22
Q

Which disease involves a mutation in a gene of chromosome 7 that encodes for an ABC transporter called CFTR?

A

Cystic fibrosis

23
Q

What are the predominant cations & anions in the ECF?

24
What are the predominant cations & anions in the ICF?
K, PO4
25
Example of impermeant solute
Glucose (effective osmole)
26
Example of Permeant solute
Urea (ineffective osmole)
27
Effective osmole used in the treatment of brain edema
Mannitol
28
Osmotic pressure from large molecules (proteins)
Oncotic pressure
29
Weight of the volume of a solution divided by weight of equal volume of distilled (pure) water
Specific gravity
30
Ca-ATPase pump in the cell membrane
PMCA
31
Ca-ATPase pump in the sarcoplasmuc reticulum & endoplasmic reticulum
SERCA
32
Functions of the Na-K-ATPase pump
Contributes to RMP; prevents cellular swelling
33
Functional subunit by Na-K-ATPase pump inhibited by cardiac glycosides
Alpha subunit
34
In all epithelial cells, Na-K- TPase pump is found in the basolateral side EXCEPT:
Choroid plexus
35
Why do RBCs swell when chilled?
Decreased ATP synthesis leads to Dec activity of Na-K-ATPase pump