Cell Physiology Flashcards
(36 cards)
Powerhouse of the cell
Mitochondria
Contains DNA, Histones & Chromosomes, has nucleolus
Nucleus
Involve in detoxification, lipid synthesis, lipid soluble substances to water soluble substances
Agranular endoplasmic reticulum (SER)
For synthesis of proteins bound for
the cell membrane, lysosomes, outside of the cell
RER Ribosomes
For synthesis of proteins bound for the cytoplasm & mitochondria
Free floating ribosomes
For packaging, molecular tagging & synthesis of hyaluronic acid & chondroitin sulfate
Golgi apparatus
Contains proenzymes, neurotransmitters & replenishes cell membrane components
Secretory vesicles
For regression of tissues & autolysis; suicide bags of cells; destroys FB
Lysosomes
Degrades membrane-associated proteins; not membrane bound
Proteosomes
Contains oxidases, catalases, for detoxification
Peroxisomes
What do you call the specialized SER in skeletal muscle?
Sarcoplasmic reticulum
What do you call the specialized RER in the neuron?
Nissl substance
The only substance modified in the RET & not the Golgi apparatus
Collagen
What is added ti lysosome-bound proteins by the Golgi apparatus?
Mannose 6-phosphate
Lysosomes come from which organelle?
Golgi apparatus
Perixisomes come from which organelle?
SER
Wear & tear pigmenta that accumulates in lysosomes
Lipofuscin
Disease with dynein missing in cilia & flagella
Kartagener syndrome
What is the explanation for the situs inversus in Kartagener’s syndrome
Defective primary cilia
What is the functional unit of the gap junction?
Connexon
What do you call the movement of substance through the apical & basolateral side?
Transcellular transport
What do you call the movement of substances between cells through tight junctions?
Paracellular transport
Which disease involves a mutation in a gene of chromosome 7 that encodes for an ABC transporter called CFTR?
Cystic fibrosis
What are the predominant cations & anions in the ECF?
Na, K