Flashcards in Cellular Physiology (Part 1) Deck (73)
Total body water accounts for how much of total body weight?
Low body fat = ___ total body water
High body fat = ___ total body water
Do males or females tend to have less body water and why?
Females, because they have a higher percentage of adipose tissue
Total body water is distributed between what 2 major body fluid compartments?
intracellular fluid and extracellular fluid
ICF is contained within the cells and constitutes how much of total body water?
ECF is outside the cells and constitutes how much of total body water?
The ECF is further divided into what 2 compartments?
- interstitial fluid
What is plasma?
the fluid circulating in the blood vessels
What is interstitial fluid?
the fluid that actually bathes the cells
Which constitutes a larger percentage of the ECF, plasma or interstitial fluid?
the interstitial fluid
What separates the ICF and ECF?
What separates the plasma and interstitial fluid?
What is the major difference between the plasma and interstitial fluid?
Because the capillary wall is impermeable to large molecules, the interstitial fluid does not contain any proteins, whereas the plasma does
One mole is 6 x 10 ^__ molecules of a substance
Amounts of a solute are expressed in what?
Concentrations of solutes are expressed in what?
moles, equivalents, or osmoles
moles per liter, equivalents per liter, or osmoles per liter (in biological solutions use milli-)
An equivalent is used to describe the amount of what?
charged (ionized) solute
one millimole is 1/___ moles
What is an osmole?
The number of particles into which a solute dissociates in solution
How do you calculate an equivalent?
multiply the number of moles of the solute by its valence (number of electrons an ion can attach to)
What is osmolality?
The concentration of particles in solution expressed as osmoles per kilogram
What is osmolarity?
The concentration of particles in solution expressed as osmoles per liter
If a solute dissociates into more than one particle in solution, then its osmolarity equals what?
the molarity multiplied by the number of particles in solution
If a solute does not dissociate in solution then its osmolarity is equal to what?
As the concentration of H+ increases, then pH _____, and as the concentration of H+ decreases, pH _____.
pH is used to express the concentration of what ion?
What is the principle of macroscopic electroneutrality?
each compartment must have the same concentration of positive and negative charges
What is normal body pH?
What is the major cation and 2 balancing anions in the ECF?
cation: sodium (Na+)
anions: chloride (Cl-) and bicarbonate (HCO3-)
Cations are ____ charged
Anions are _____ charges
Is the ICF or ECF more acidic (lower pH)?