Cephalosporins Flashcards Preview

Z A Pharm III > Cephalosporins > Flashcards

Flashcards in Cephalosporins Deck (10):
1

What is the cephalosporins MOA

interfere cell wall synthesis

2

What is the bacterial MOR to cephalosporins

B-lactamase but not as effective as against penicillin

3

What are the types of cephalosporin

1st gen - good G +
2nd gen - fair G+ and G-
3rd gen - good G -

4

What are 1st gen cephalosporins

Cephalexin
Cefazolin
- skin and bone infections
- UTI

5

What are 2nd gen cephalosporins

Cefuroxime
Cefoxitin
- CAP
- sinusitis
- AECB
- otitis media
- UTI

6

What are the 1st gen cephalosporins good at treating

strep (no pneumonia)
staph
EKP

7

What are the 2nd gen cephalosporins good at treating

staph
strep
G -
EKP
anaerobes
clostridium

8

What are 3rd/4th gen cephalosporins

Cefpodoxime
Ceftriaxone + (Vancomyocin)
- 1-2g IV 24hr
- Meningitis
- 2g IV q12hr
Ceftazidime

9

what are 3rd/4th gen cephalosporins good at treating

staph
strep
G -
EKP
ES
pseudomonas

10

What are adverse effects for cephalosporins

hypersensitive to penicillin and self
diarrhea
platelet dysfunction
neutropenia