Influenza, Anthrax, SARS Flashcards Preview

Z A Pharm III > Influenza, Anthrax, SARS > Flashcards

Flashcards in Influenza, Anthrax, SARS Deck (27):
1

What are the txt for Influenza

Oseltamivir (Tamiflu)
Zanamivir (relenza)
Amantadine (Symmetrel)
rimantadine (Flumadine)

2

When do you use Oseltamivir

treat influenza in pts >= 2 weeks old
symptoms less than 2 days

3

When do you use Oseltamivir prohylaxisly

in pts > 1 yr

4

What is Oseltamivir MOA

inhibit virus enzymes

5

What is efficacy of Oseltamivir if started within 24 hrs of onset

reduced symptoms by 1 day

6

What is efficacy of Oseltamivir if started within 12 hrs of onset

reduced illness by 74.6 hrs

7

What are adverse effects of Oseltamivir

Tx:
Insomnia
vertigo
N/V

Prophylax:
HA
fatigue
cough
diahrrea

8

What is dosage of Oseltamivir

75 mg po bid 5 days

9

When do you use Zanamivir

treat influenza in pts >= 7 yrs
symptoms less than 2 days

10

When do you use Zanamivir prohylaxisly

in pts >= 5 yrs

11

What is Zanamivir MOA

inhibit virus enzymes

12

What is efficacy of Zanamivir

relieved symptoms 1.5 days earlier

13

What are adverse effects of Zanamivir

HA
D/N/V
dizziness
bronchospasm

14

What is dosage of Zanamivir

2 inhalations bid x 5

15

When do you use amantadine or rimantadine

Influenza A

16

What is MOA for amatadine or rimantadine

block uncoating of Influenza A virus

17

What are adverse effects of amatadine or rimantadine

Nervousness
anxiety
Nausea
anorexia
behavior changes

18

What is dosing of amatadine or rimantadine

100 mg po bid

19

How does SARS spread

droplet transmission

20

What is the etiology of SARS

SARS-associated coronavirus

21

What is SARS incubation

2 - 10 days

22

What are symp of SARS

dry cough
SOB
URT symptoms
Xray confirmed pneumonia
lymphopenia

23

How txt SARS

supportive
treat as CAP until confirmed

24

What is anthrax etiology

Bacillus antracis
G+ spore

25

What are types of anthrax infection

Cutaneous
Gastrointestinal
Inhalation

26

What are txt inhalation anthrax

treat 60 days

Cipro or Levo
or
doxycycline

and

clindamycin and/or rifampin

27

How txt anthrax prophylaxis

Cipro or Levo or doxycycline
Move to amoxicillin when can