Cerebellum Flashcards

1
Q

how many lobes in the cerebullum

A

3

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2
Q

what are the 3 lobes in the cerebellum

A

anterior, posterior, and flocculondoular

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3
Q

What are the 4 rules of 3 in the cerebellum

A

3 functional subdivisions, 3 pairs of peduncles, 3 pairs of deep nuclei and 3 cortical layers

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4
Q

what are the 4 functions of cerebullum

A

Movement coordination, maintenance of posture, maintenance of muscle tone and balance, motor learning

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5
Q

what percentage of neurones in the cerebellum

A

80%

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6
Q

where is the cerebellum situated

A

posterior brainstem

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7
Q

what does the cerebellum integrate

A

sensory input and motor outputs making it an ideal location for motor learning

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8
Q

damage to the cerebellum causes..

A

severe movement disruption but not complete movement abolition-

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9
Q

what is axtia

A

abnormal execution of multi jointed voluntary movements (n lack of coordination)

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10
Q

what can axtia be caused by

A

stroke, multiple sclerosis and tumor/ brain damage

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11
Q

what are the 3 deep cerebellar nuclei

A

denate, interposed and fastigial nucleus

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11
Q

what is a penduncle

A

a large bundle of neurons that are in the shape of a stalk

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11
Q

What are the 3 cerebullar penduncies

A

superior, middle and inferior

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11
Q

what are the 3 cerebellar cortex

A

cerebrocerebellum, spinocerebellum, vestiobulocerebellum

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11
Q

the cerebellum is connected to the what aspect of the brain stem

A

dorsal

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11
Q

the cerebellum is connected to the dorsal brainstem by what

A

3 symmetrical pairs of peduncles

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12
Q

state the 2 facts about the superior peduncle

A

no input and output to motor cortex - via thalamus and red nucleus

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13
Q

state 2 facts about middle peduncle

A

no outputs, inputs from motor cortex via pons.

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14
Q

state 2 facts for inferior peduncle

A

inputs from the inferior olivary nucleus, spinal cord, and vestibular nuclei, outputs to reticular formation - brainstem, spinal cord, and vestibular nuclei.

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15
Q

what does the cerebellar cortex do

A

integrates inputs from the cortex, brainstem and spinal cord and regulates motor outputs.

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16
Q

what are the 2 inputs for cerebrocerebellum

A

pons, from motor cortex - via thalamus
inferior olive, motor c. and via red nucleus and spinal cord

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17
Q

what is the output for cerebrocerebellum

A

denate nucleus , to motor c. via thaalmus

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18
Q

what does the corocerebellum do

A

involved in motor planning and projects to and from the cerebral, (motor cortex)

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19
Q

cerebrocereebllum is the what hemisphere

A

lateral ( located on the bottom)

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20
what 2 parts comprise the spinocerebellum
vermis and intermediate cortex
21
what does the spinocerebellar do
regulates body and limb movements
22
what are the 2 input for spinocerebellum
vermis - head and trunk and intermediate cortex - limbs
23
where is the spinocerebellar located in the cerebellar cortex
at the top
24
what are the 2 inputs for the spinocerebellum
Vermis - [spinal cord carrying sensory info. from trunk and head intermediate cortex - spinal cord carrying sensory info. from limbs
25
what are the 4 out puts for spinocerebellum
vermis - fastigial nucleus to medial descending tracts - reticulospinal and vestibulospinal tracts and motor execution intermediate cortex- motor planning and lateral descending tracts of corticospinal and rubrospinal tracts
26
what is the output for vestibulocerebellum?
vestibular nucleus to axial and proximal muscles - limb extensors and head and eye muscles
27
what is the input for vestibulocerebellum
vestibular nucleus from semicircular canals and otolith organs
28
what is the other name for vestiobulocerebellum
flocculondular lobe
29
what does the vestiobulocerebellum do
regulates balance and eye movements
30
what are the 3 deep cerebellar nuclei
fastigial, denate and interposed
31
where is denate nuclei located
cerebrocerebellum
32
where is the deep interposed nuclei located
intermediate cortex
33
where is the fastigial deep nuclei located
vermis in spinocerebellum
34
what is the output for fastigial deep nuclei
to the reticular formation and vestibular nucleus via inferior peduncle
35
what is the output for denate deep nuclei
motor cortex via superior peduncle and thalamus
36
what is the output for the interposed deep nuclei
red nucleus via superior peduncle
37
where does the cerebellar cortex receive input from (3)
pontine nuclei, inferior olive (climbing fibers only ) spinal cord and vestibular nuclei.
38
what are the 3 cerebellar cortex outputs
cerebrocerebellum - denate nucleus spinocerebellum - interposed and fastigial nuclei vestiobulocerebellum- vestibular nuclei
39
what is the 3 points of out puts for cerebrocerebellum
cerebrocerebellum - denate nucleus - premotor cortex - motor planning
40
what are the 3 points of outputs ofr spinocerebellum
spinocerebellum - interposed and fastigial nuclei
41
what are the 3 ouputs for vestiobulocerebellum
vestiobulocerebellum- vestibular nuclei- neurons in the spinal cord and brainstem (balance and vestibulo-ocular regulation)
42
what are the 5 elements in cerebellar circuitry
mossy fibers, granule cells, climbing fibers, Purkinje cells and parallel fibres
43
how many layer re there in the cerebellar circuitry
3
44
what are the 3 layers in the cerebellar circuity
granule, Purkinje and molecular
45
what layer in the cerebellar circuity is deep to superficial
deepest is granule layer and most superficial is molecular
46
what type of fibres crosses a purkinje cell
parallel fibres
47
dendrite receive afferent information from what 2 fibres
climbing and parallel
48
what is the output of purkinje cells
deep cerebellar nuclei
49
what is the ratio of input for purkinje cells
40:1 input to output
50
what is the function of purkinje cells
release a NT called GABA, which inhibits neurons and reduces transmission of nerve impulses - they control/ coordinate and regulate movement ----- inhibit
51
what are mossy fibres
primary neurons that carry information into cerebellum can activate granule cells and cerebellum nuclei
52
granule cells attach to what type of fibre
parallel fibres
53
after the granule cell and parallel fibres attach, what occurs
they synapse with dendrites of Purkinje cells
54
what occurs when the Purkinje fibres are activated
inhibit cerebellar nuclei which modulates motor output
55
the climbing fibre does what
excites the Purkinje cells directly (can sense signals to elicit learning)
56
the eye blink response is an example of what
cerebellum sensorimotor learning
57
what are major inputs via
mossy and climbing fibres
58
cerebellum receives inputs from where
the brainstem and spinal cord
59
cerebellum outputs go where
thalamus and brainstem
60
climbing fibre activation leads to what
learning by changing Purkinje cell response to mossy fibre input
61