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Flashcards in Cerebellum Deck (72)
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1

What is the function of the cerebrocerebellum?

it modulates cortices involved in movement

2

The spinocerebellum contains the _____.

vermis and paravermis

3

What is the function of the paravermal zone?

stretch and withdrawl reflexes

4

Name the 4 deep cerebellar nuclei.

  1. Dentate nucleu
  2. Globose
  3. and emboliform which together make the interposed nucleus
  4. Fastigial Nuclei

5

Small lesions of the cerebellum have _____ effects.

little

6

What is the function of the interposed nucleus?

it fine tunes movements of the limbs

7

Lateral cerebellar lesions impair _____.

the ipsilateral limb

8

What are the 3 layers of the cerebellar cortex?

  1. molecular layer -->
  2. Purkinje layer -->
  3. internal granular layer --> (white matter --> deep cerebellar nuclei)

9

Name the 3 deep cerebellar nuclei (principal outputs from the cerebellum).

  1. dentate nucleus (most lateral)
  2. interposed nucleus
  3. fastigial nucleus (most medial)

10

This zone of the cerebellum modulates cortices involved in movement.

the cerebrocerebellum

11

Name the cerebellar functional zone: vestibular nuclei

the vestibulocerebellum pathway

12

Parallel fibers from granule cells converge on _____.

Purkinje cells

13

The granule cells relay the mossy fiber info thru the _____ to the _____.

parallel fibers --> Purkinje cells

14

What is the function of the dentate nucleus?

planning, initiation and coordination of voluntary movements

15

What is the function of the fastigial nucleus?

control of axial musculature, posture, balance and integration of head and eye movements

16

What are the 3 lobes of the cerebellum?

  1. the floculonodular lobe
  2. the anterior lobe
  3. the posterior lobe

17

What is the output of the cerebrocerebellum pathway?

the contralateral VA/VL thalamus (and red nucleus)

18

This zone of the cerebellum has control of axial skeleton and vestibular control (balance, eye movements).

the vestibulocerebellum

19

Inhibitory interneurons connecting the neighboring Purkinje cells facilitates _____.

lateral inhibition

20

What is the output of the spinocerebellum vermis pathway?

fastigial nucleus --> medial decending tracts

21

How many parallel fibers contact an individual Purkinje cell?

TONS!

22

_____ cerebellar lesions impair the ipsilateral limb.

Lateral

23

What is the Purkinje cell response to excitation by a granule cell?

a simple spike

24

Climbing fibers have a _____ excitation than the mossy fibers, and the Purkinje cells respond with a ______.

stronger --> complex spike

25

Name the cerebellar functional zone: fastigial nucleus --> medial decending tracts

spinocerebellum vermis pathway

26

Name the cerebellar functional zone: the lateral decending tracts and RED NUCLEUS

the spinocerebellum paravermis pathway

27

What is the function of the flocculonodular lobe?

  • axial control and balance
  • eye movement
  • the vestibuloocular reflex
  • vestibule-colic reflex
  • vestibule-spinal reflex

28

What are the inputs to the cerebellum?

  • contralateral cortex --> middle cerebellar peduncle --> cerebellum
  • ipsilateral proprioceptive info from spinal cord --> inferior cerebellar peduncle --> mossy fibers --> cerebellum as a copy of the reflex input
  • contralateral proprioceptive info from spinal cord --> inferior olivary nucleus (ION) --> climbing fibers --> cerebellum as an error signal of unexpected response

29

Cerebellar defects are ALWAYS _____.

ipsilateral (they're either uncrossed or cross twice)

30

Climbing fibers innervate which functional zones of the cerebellum?

all 3: the vestibule, spino, and cerebrocerebellum