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Flashcards in Cervical CA Deck (23):
1

most cervical CA is of what cell type?

squamous cell

2

most squamous cell cervical CA is related to what virus?

HPV

3

20% of cervical CA are of what cell type?

adenocarcinoma

4

adenocarcinoma of the cervix is mainly of what etiology?

maternal DES exposure (diethylstilbestrol)

5

how is cervical CA staged?

clinically

6

mucus-filled cyst on the surface of the cervix

nabothian cysts (as per Couli, most common lesion on the cervix)

7

mets of cervical CA is most likely where?

RIB Eye (rectal, intra peritoneal, bladder, endometrial) .. remember the hematogenous spread is BLBL (breast, lung, bone, liver)

8

what is removed during a radical hysterectomy?

uterus, cervix, parametrial tissue and upper vagina

9

what is the treatment for invasive cervical CA?

radical hysterectomy w/lymph node dissection

10

for which stage of cervical CA is a radical hysterectomy recommended?

low stages

11

in terms of follow-up care of cervical carcinoma, what is the protocol? (be specific!)

PE every three months for the first 2 yrs then every 6 months for year 3-5 and then annually; PE includes: pap, chest x-ray, and ct scan of abdomen

12

t or f: approximately 30% of pts treated for cervical CA will have recurrence

TRUE - typically it returns in the pelvis

13

in addition to vaginal bleeding, pelvic and leg pain - what is one other sign that should trigger you to think recurrence of cervical CA?

sacral backpain/ache in sciatic distribution

14

what is the major cause of death in cervical CA?

uremia due to periuretal compression of the tumor

15

t or f: 1/3 of pregnant patients with cervical CA are asymptomatic

TRUE

16

what is the basic treatment for invasive cervical CA if confined to the cervix?

radical hysterectomy w/ pelvic lymphadenectomy; if beyond the cervix, chemo and radiation

17

t or f: therapeutic conization is contraindicated in pregnancy

TRUE

18

t or f: ECC is contraindicated in pregnancy

TRUE

19

t or f: chemotherapy is contraindicated in pregnancy, but radiation is OK

FALSE; radiation is contraindicated, but chemotherapy is acceptable for treatment of cervical CA`

20

in terms of cervical CA and delivery, @ what stage are patients candidates for vaginal delivery?

early small volume stages - when @ greater stages, pt must get c section

21

what is the average age of a pt with adenocarcinoma of the cervix?

16-27 years old

22

what is the treatment of adenocarcinoma of the cervix?

radical hysterectomy and pelvic lymph node dissection

23

t or f: most DES-related CA recur within three years of initial treatment?

TRUE