Ch. 11 Minerals and Bone Health Flashcards

1
Q

minerals: ________ elements needed by the body in ____ for health/maintenance

A

inorganic (non-carbon), small amounts

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2
Q

major minerals are needed in the diet in amounts greater than ____ per day or in body in amounts _______

A

100mg, greater than 0.01% of body weight

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3
Q

major minerals

A

Na, Mg, K, Ca, P, S, Cl

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4
Q

trace minerals are required in the diet in amounts less than ___ or present in body in amounts ______

A

100mg, less than 0.01% of body weight

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5
Q

trace minerals

A

F, Si, Cr, Mn, Fe, Ni, Cu, Zn, Mo, I, etc.

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6
Q

bioavailability is the amount of a substance that is released from ____, ___ in the ____, and available for the body to use by ______

A

food, absorbed/GI tract, cells and tissues

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7
Q

is bioavailability the same or different for each mineral?

A

different

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8
Q

additional factors affecting mineral bioavailability

A
  • dose
  • chemical form
  • food matrix
  • coingestion of other nutrients
  • compounds binding minerals
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9
Q

cofactors are needed to _______ and _____

A

activate enzymes, catalyze reactions

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10
Q

minerals (are/are not) essential cofactors in many metabolic processes

A

are

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11
Q

bone structure: ____ matrix with _______ crystals to support it

A

collagen (protein), hydroxyapatite

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12
Q
\_\_\_\_\_ = hard outer shell 
\_\_\_\_ = spongy inner bone
A

cortical bone, trabecular bone

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13
Q

cortical bone is ___% of total bone mass; trabecular is __%

A

80%, 20%

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14
Q

cortical bone serves are main _____ for body weight and _____

A

structural support, protects organs

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15
Q

trabecular bone has a _________ and supers of support for _____

A

higher surface area, mechanical stress

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16
Q

bone is a ______ tissue

A

living/dynamic

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17
Q

adult skeleton is completely remodeled every _____

A

10 years

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18
Q

bone remodeling is the result of _______, and older bone becomes more ____

A

osteoclast/osteoblast, fragile

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19
Q

brittle bone disease, defined by having
significant losses in bone mass that makes individual
more susceptible to fragility fracture

A

osteoporosis

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20
Q

osteoporosis is calculated using a ____

A

T-score

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21
Q

T-score is compared to _____ while Z-score is compared to _____

A

optimum bone mass, age-matched controls

22
Q

dietary sources of calcium (top 3)

A

yogurt, milk, cheese

23
Q

calcium deficiency symptoms

A
  • reduced bone mass
  • osteoporosis/fractures
  • osteomalacia
24
Q

calcium toxicity

A
  • GI distress
  • confusion/coma/death
  • possibly CVD, some cancers
25
Q

what is the most abundant mineral in the body?

A

Ca

26
Q

function of blood calcium

A

nerve transmission, muscle contraction, BP regulation, hormone release

27
Q

___ __% of ingested Ca is absorbed and bioavailable

A

only 30%

28
Q

Ca absorption uses ____ and _____

A

active transport (requires vitamin D), passive diffusion

29
Q

Ca has a ____ with higher dose

A

decreased % absorption

30
Q

low concentrations of Ca require ____; high can use ____

A

active transport, passive diffusion

31
Q

dietary sources of phosphorus

A

yogurt, canned sardines, sunflower seeds

32
Q

Phosphorus deficiency can lead to _______

A

bone loss, weakness, loss of appetite

33
Q

phosphorus toxicity is _____ but can lead to _____

A

rare, bone resorption

34
Q

phosphorus makes up about __% of an adult’s body; ___% of that is found in ___

A

1%, 85%, bones/teeth

35
Q

phosphorus functions

A
  • bone
  • phospholipids
  • DNA/RNA
  • energy metabolism (ATP)
36
Q

phosphorus absorption mechanism…

A

via passive diffusion, some active transport

37
Q

_______ are highly bioavailable

A

phosphate additives

38
Q

dietary sources of Mg

A

cooked spinach, sunflower seeds, almonds

39
Q

Mg deficiency is _____

A

rare, but occurs in indv with alcoholism/malnutrition/kidney and GI disease

40
Q

Mg deficiency may cause…

A

nausea, muscle weakness, mental derangement, BP and heartbeat changes

41
Q

Mg toxicity is ____ and causes ____

A

rare, GI distress and possible hypotension/facial flushing

42
Q

adults typically have ~___g of Mg; ____% found in bone; Mg is a cofactor in over ____ enzymes

A

25g, 50-60%, 300+

43
Q

Mg bioavailability is ___%

A

25-70%

44
Q

sulfur is found is ______ and _____

A

protein foods, sulfur-containing AA in vitamins

45
Q

the vitamins ____ and _____ contain sulfur

A

thiamin, biotin

46
Q

RDI for sulfur

A

there is no recommended daily intake for sulfur

47
Q

high blood calcium triggers the release of ____ from the ____

A

calcitonin, thyroid gland

48
Q

calcitonin function

A

inhibits calcium release from bone

49
Q

recommended intake for adults: Ca

A

1000-1200 mg/day

50
Q

recommended intake for adults: P

A

700mg/day

51
Q

recommended intake for adults: Mg

A

310-420 mg/day

52
Q

recommended intake for adults: S

A

none specified