Ch 15 Flashcards Preview

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Flashcards in Ch 15 Deck (14):
1

What is the most common mode of transmission with the G.I. tract?

Contaminated food and water

2

What is a Parenteral route?

Go through the skin and into the dermis, such as a bite, stab, needle puncture, scrapes, etc.

3

LD50

Lethal Dose
Toxin production, not the infection
Most potent toxins as the lowest LD50
More exact

4

Units for LD50?

Nanogram (ng) or milligram(mg) over kilogram (kg)

5

ID50

Infectious Dose
Using animal models, how many microbes did it take to get half of that population sick with the disease

6

Capsule:
What merges with the phagosome?

Lysosome, and end up with phagolysosome

7

If you're a bacteria and produce Coagulase, what advantage would that be?

You can surround with the clot, live within the clot so that the defense can't get you

8

What's the advantage of kinase?

* Have access to the bloodstream to spread to new tissues and organs
* Cam go systemic and relocate around the body

9

Where are ferritin proteins made?

The liver

10

What do siderophores do?

Bind free iron in the blood
Fe^2+ and Fe^3+

11

Why do siderophores want to bring the iron into the cell?

Iron is an important cofactor for bacterial enzymes so they need it so their enzymes can function properly

12

Ruffling

Where the bacteria alter the apical surface of the cell as they're entering. They are changing the entire shape of the cell at the area that they're using for entry and once they get inside to so they can secrete enzymes and kill the cell

13

What do you T cells do?

They secrete a variety of toxic compounds

14

What do the compounds of the T cells do?

They induce inflammation and they damage host cells