Flashcards in Ch 15 Deck (14):
What is the most common mode of transmission with the G.I. tract?
Contaminated food and water
What is a Parenteral route?
Go through the skin and into the dermis, such as a bite, stab, needle puncture, scrapes, etc.
Toxin production, not the infection
Most potent toxins as the lowest LD50
Units for LD50?
Nanogram (ng) or milligram(mg) over kilogram (kg)
Using animal models, how many microbes did it take to get half of that population sick with the disease
What merges with the phagosome?
Lysosome, and end up with phagolysosome
If you're a bacteria and produce Coagulase, what advantage would that be?
You can surround with the clot, live within the clot so that the defense can't get you
What's the advantage of kinase?
* Have access to the bloodstream to spread to new tissues and organs
* Cam go systemic and relocate around the body
Where are ferritin proteins made?
What do siderophores do?
Bind free iron in the blood
Fe^2+ and Fe^3+
Why do siderophores want to bring the iron into the cell?
Iron is an important cofactor for bacterial enzymes so they need it so their enzymes can function properly
Where the bacteria alter the apical surface of the cell as they're entering. They are changing the entire shape of the cell at the area that they're using for entry and once they get inside to so they can secrete enzymes and kill the cell
What do you T cells do?
They secrete a variety of toxic compounds