bacteriophage
a virus that infects bacteria
mismatch repair
when cells use special enzymes to fix incorrectly paired nucleotides
telomeres
nucleotide sequences at the end of eukaryotic chromosomal dna used to postpone the gradual destruction of genes near the ends of dna molecules
telomerase
accelerates the lengthening of telomeres in germ cells
snRNPs
ribonucleoproteins: recognize the splice sites
ribozymes
rna molecules that functions as enzymes and can splice rna
UTR
untranslated region: the section of mrna that immediately follows the translation termination codon
domains
discrete structural and functional regions of a protein
aminoacyl-trna synthetase
joins each amino acid to the correct trna
wobble
relaxation of base pairing rules
polyribosomes
the number of ribosomes that can translate single mrna simultaneously
post translational modification
Insulin: starts as single polypeptide chain, becomes active after central part is cut out of the chain so it is now 2 polypeptide chains
mutation
change in genetic material of cell or virus
point mutation
chemical change in 1 base pair of a gene
base pair substitution
replaces 1 nucleotide and its partner with another pair of nucleotides
missense mutation
when a codon still codes for an amino acid but may not always be the right one
nonsense mutation
change in amino acid codon into a stop codon that usually leads to a nonfunctional protein
mutagen
physical or chemical agent that causes a mutation
cell differentiation
process where a generic cells turns into a special cell
histone acetylation
promotes transcription by modifying chromatin structure
histone deacetylation
decreases transcription
dna methylation
decreases transcription
epigenetic inheritance
the inheritance of traits transmitted by mechanisms not directly involved in the nucleotide sequence
rna interference
when double stranded rna can turn off genes with the same sequence