ch 17 Flashcards

1
Q

viruses characteristics

A

non motile, rna or dna, acellular, visible under electron microscopy, not alive, small asf, abundant

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2
Q

capsid

A

portion coat, may have spikes

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3
Q

obligate intracellular parasite

A

must replicate inside host

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4
Q

what can viruses infect

A

all living organisms

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5
Q

strains

A

differ in virulence and antigenic properties

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6
Q

varient

A

altered genotype, but does same thing

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7
Q

virus classified

A

host, size and shape, envelope, nucleic acid, disease caused

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8
Q

host range is determined by

A

specific host attachment sites and cell factors for multiplication

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9
Q

zoonosis

A

animal virus that jumps to human

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10
Q

virion

A

ready to infect host cell

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11
Q

virion parts

A

nucleic acid- DNA/RNA, singe or double, linear or circular
protein coat- capsid
envelope- extra capsid layer (maybe), from host

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12
Q

nuceleocapsid

A

nucleic acid plus capsid

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13
Q

spikes on viruses are - for -

A

spiky protein for attachment

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14
Q

capsid shapes

A

icosahedral or helical

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15
Q

enveloped viruses appear

A

spherical

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16
Q

how to viruses acquire envelopes

A

steal plasma membrane and proteins from host

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17
Q

budding

A

developing a virion

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18
Q

complex viruses

A

capsid with additional structures
ex bacteriophage

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19
Q

helical virus

A
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20
Q

polyhedral virus

A

Many sided – 20 equilateral triangular faces
– Example: adenovirus and poliovirus

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21
Q

virions encode info to make proteins for

A

structure, attachment, replication modifications of nucleic acids

22
Q

class I

23
Q

class II

24
Q

class III

25
class IV
+ssRNA
26
class V
-ssRNA
27
class VI
ssRNA-RT
28
class VII
dsDNA-RT
29
positive nucleic acid polarity
virus can act as mRNA
30
-viridae
virus family name
31
viral species
"common name" group of viruses sharing the same genetic info and ecological niche
32
virus infection cycle
1.attachment/absorption 2.entry- fusion/endocytosis 3. uncoating 4. biosynthesis- make parts 5. maturation- assemble 6.release
33
eclipse periods
bn attachment and release
34
If host has high glucose, virus will be
lytic (replicate in cell, take over, go crazy)
35
If host has low glucose, virus will be
lysogenic (incorporate into genome)
36
animal virus cell attachment
bind to receptor on host (glycolipids or glycoproteins)
37
dsDNA virus
use host cell machinery directly, need to enter nucleus
38
episomes
circular DNA, virus genome integrated into host DNA
39
ssDNA
use host cell machinery directly, replicates ssDNA to dsDNA, ssDNA for progeny
40
dsRNA
need RNA replicase replicated as dsRNA
41
ssRNA
need RNA replicase ssRNA- template to make ssRNA+ for progeny occurs in cytoplasm
42
release via
budding or rupture
43
easiest ways to repent viral infection
behavior and vaccination
44
antivirals
not many, target unique viral structure
45
RNA virus mutation rate
higher than DNA viruses
46
drugs (3) that target HIV inhibit
intergrase, entry, reverse transcription, protease
47
detecting viruses via counting
grow and look for plaques and cytopathic effects
48
negri bodies (for rabies and such)
staining inclusion
49
serotyping
antibody test for antibodies
50
molecular methods for viral detection
DNA hybridization, PCR, RT-PCR
51
Genus names end in
-virus
52
treating viruses
Preventing infections (best option?) – Vaccination – Behavior AND DRUGS THAT TARGET STRUCTURE