Ch. 18 & 19 - Autonomic Nervous System Agents Flashcards Preview

Pharmacology > Ch. 18 & 19 - Autonomic Nervous System Agents > Flashcards

Flashcards in Ch. 18 & 19 - Autonomic Nervous System Agents Deck (31):
1

adrenergic agonists - drugs that stimulate the sympathetic nervous system

Sympathomimetics

2

alpha1, alpha2, beta1 & beta2 receptors

Adrenergic Receptors

3

chemical structurs of a substance that can produce a sympathomimetic response

Catecholamines

4

acting on different adrenergic receptors

Nonselective

5

acting on one adrenergic receptor (EX: albuterol)

Selective

6

drugs that block the effects of adrenergic neurotransmitters..."sympatholytics"

Adrenergic Blockers (Antagonists)

7

drugs that block/inhibit a response at the alpha-adrenergic receptor site

Alpha-Blockers

8

drugs that block/inhibit a response at the beta-adrenergic receptor site

Beta-Blockers

9

drugs that stimulate the parasympathetic nervous system

Cholinergic Agonists ("Cholinergics" or "Parasympathomimetics")

10

neurotransmitter located at the ganglions and the parasympathetic terminal nerve endings

Acetylcholine (ACh)

11

receptors in the parasympathetic nervous system that stimulate smooth muscle and slow the heart rate

Muscarine Receptors

12

receptors in the parasympathetic nervous system that affect the skeletal muscles

Nicotinic Receptors

13

drugs that act on cholinergic receptors to activate a tissue response

Direct-Acting Cholinergic Agonists

14

drugs that inhibit or inactivate the action of the enzyme cholinesterase (ChE)

Indirect-Acting Cholinergic Agonists

15

drugs that inhibit cholinesterase (ChE)

Anticholinesterases ("Cholinesterase Inhibitor" or "Acetylcholinesterase (AChE) Inhibitors")

16

enzyme that catalyzes the hydrolysis of choline esters, such as acetylcholinesterase, which catalyzes the breakdown of acetylcholine to acetic acid & choline

Cholinesterase (ChE)

17

constricting of the pupils of the eyes

Miosis

18

drugs that inhibit the actions of acetylcholine by occupying the acetylcholine receptors

Anticholinergics ("Parasympatholytics or "Cholinergic Blocking Agents")

19

dilation of the pupils

Mydriasis

20

Actions of Adrenergic Agonists (Sympathomimetics)

vasoconstriction, increase HR, increase BP, dilate pupils (mydriasis), increase bladder & prostate contractions, decrease GI motility, dilate bronchioles, relax uterus, increase blood sugar

21

Uses for Adrenergic Agonists (Sympathomimetics)

anaphylaxis, shock, asthma, congestion (alpha1), decrease BP (alpha2)

22

Actions of Adrenergic Blockers (Sympatholytics)

vasodilation, decrease BP, decrease HR, constrict pupils (miosis), decrease bladder & prostate contractions

23

Side Effects of Adrenergic Agonists (Sympathomimetics)

pulmonary edema, urinary retention, dyspnea, hypertension, tachycardia, palpitations, restlessness, tremors, dysrythmias, dizziness, N&V

24

Uses for Adrenergic Blockers (Sympatholytics)

decrease BP, decrease HR, glaucoma (beta)

25

Side Effects of Adrenergic Blockers (beta blockers)

bradycardia, hypotension, headache, dizziness, cold extremities, dysrythmias, flushing, weakness, impotence, depression, pulmonary edema

26

Actions of Cholinergic Agonists (Parasympathomimetics)

vasodilation, decrease HR, increase perstalsis/salivation, stimulate bladder & GI, constrict pupils (mydriasis), increase neuromuscular transmission

27

Uses for Cholinergic Agonists

Alzheimer's (increased cognitive function), mysthenia, Gravis (increased muscular strength), glaucoma, WMD

28

Side Effects of Cholinergic Agonists

hypotension, bradycardia, blurred vision, excessive salivation, increased gastric secretions, abdominal cramps, diarrhea, bronchoconstriction, dysrythmias

29

Actions of Anticholinergics (Parasympatholytics)

increase HR, decrease peristalsis/salivation, decrease GI motility, dilate pupils, decrease tremors & rigidity of muscles

30

Uses for Anticholinergics

increase HR (atropine), decrease secretions (pre-op), Parkinsonism

31

Side Effects of Anticholinergics

dry mouth, decreased perspiration, blurred vision, tachycardia, constipation, urinary retention