Ch 26 - Fluid Balance Flashcards

(50 cards)

1
Q

fluid, electrolyte, and acid base balance is

A

water in the body, water movement, and 7.35-7.45

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2
Q

most water exists where and how much

A

ICF, 66%

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3
Q

how much water is in ECF

A

33%, has two sub compartments

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4
Q

2 compartments of the ECF

A

plasma, non living
interstitial fluid, living (lymph, CSF, humors, serous fluid, and synovial fluid)

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5
Q

body fluids are composed of

A

electrolytes and non electrolytes

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6
Q

electrolytes are

A

anything that dissociates into ions in water, has pos or neg charge, most abundant is solutes. more responsible for fluid shifts or movement of water/ INORGANIC SALTS, ACIDS BASES N SOME PROTEINS

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7
Q

why are electrolytes more responsible for fluid shift/water movement

A

bc of the dissociation, water cares for number of solute and going high to low. EX NaCl will dissociate and make stuff move

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8
Q

non electrolytes

A

do not dissociate in water, no charge, make up body fluid bulk. ex; glucose, urea, lipids

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9
Q

for Important electrolytes to keep track of

A

Na+, K+, HCO3-, Cl-

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10
Q

where is Na+ most concentrated

A

ECF

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11
Q

where is K+ most concentrated***

A

ICF

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12
Q

HCo3- most concentrated where

A

ECF

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13
Q

Cl- mostly concentrated where

A

ECF

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14
Q

changing osmolarity of one compartment leads to what

A

net water flow, water moves freely but solutes do not. ECF and ICF will keep solutes where they are so water won’t move

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15
Q

optimal body water content depends on

A

age, body mass, sex, body fat %

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16
Q

age and body water content, sex and body fat too

A

age- infants and kids have more water they need it to grow
sex- males have more water bc testosterone and muslce growth
body fat- adipose is least hydrated of tissues, less water in fat ppl

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17
Q

water intake comes from

A

ingested food and liquid as well as metabolic water.

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18
Q

metabolic water

A

32 ATP and 6 water from this

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19
Q

insensible water loss

A

lungs and skin, water vapor

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20
Q

sensible water loss

A

sweat, urine, feces

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21
Q

should water intake = water output

A

yes, when properly hydrated

22
Q

why is it important for water intake = water output

A

bc allows body to maintain 300 mOsm osmolality

23
Q

hypothalamic thirst center controls what

A

the thirst mechanism

24
Q

what is the thirst mechanism activated by

A

-osmoreceptors, which detect changing ECF osmolality
-dry mouth, salivary glands cannot draw water from blood to produce saliva
-decreasing BV and BP 5-10% drop initiates thirst mechanism, baroreceptors send information

25
high osmolality means
thirsty person
26
why is it so important that feelings of thirst cease when we drink water
bad to be dehydrated or over hydrated, it is so we do not over hydrate bc BV and BP will increase too much
27
obligatory water loss is
body will always lose water, even if we never drink water.
28
why do we have obligatory water loss
insensible water loss, kidneys never stop functioning. kidneys pull that water out so that we cannot stop water filtration
29
ADH does what
causes aquaporins to be inserted into collecting ducts. with no ADH there are no aquaporins
30
osmoreceptors do what
in hypothalamus they monitor osmolality of ECF to inhibit or stimulate ADH release
31
baroreceptors do what
monitor BP to inhibit or stimulate ADH release
32
central diabetes insipidus
decrease in ADH produced by hypothalamus or released by posterior pituitary. symptoms include polyuria and dilute urine, as well as fatigue and dehydration
33
nephrogenic diabetes insipidus
ADH is produced and released in. normal amounts but kidneys are not responsive. same result as central. similar symptoms too but also overhudration
34
importance of electrolyte balance
influence water movement in body, essential for excitability membrane permeability salt intake come from diet mostly but also some from metabolic process.
35
which two electrolytes contribute to 280 mOsm of 300 mOsm
NaHCO3 and NaCl
36
why are NaHCO3 and NaCl key players in ECF volume
bc they make up so much of the mOsm
37
NaHCO3 and NaCl
establish osmotic gradient bc water flows with Na plasma membranes are impermeable to Na and are almost always kept out of cells and in ECF
38
changing Na levels will
affect blood plasm volume and blood pressure bc sodium drags water with it
39
most Na is reabsorbed where
in PCT and nephron loop (85%)
40
aldosterone
release causes increased reabsorption of Na+ in DCT and collecting ducts. aldosterone increase means ECF will increase too
41
atrial natriuretic peptide ANP
release causes decreased reabsorption of Na+, its diuretic and natriuretic
42
sex hormones
estrogen exerts similar effect as aldosterone, Na+ brings the water, progesterone's Lowkey a diuretic
43
glucocorticoids
regulate stress, in high plasma levels it exerts very strong aldosterone like effects which contribute to edema. so kinda like ADH but need a lot to see that happen
44
hypernatremia
Na+ serum value is over 145 mEq/L caused by dehydration and excessive IV NaCl fluid effects are thirst, twitching n convulsions, confusion n lethargy can lead to coma or death basically prolongs APS so they go crazy
45
hyponatremia
Na+ serum value is below 135 mEq/L caused by overyhydration, excessive solute loss or water loss, severe burns, excessive ADH release, aldosterone deificency, renal disease or failure effects are confusion, giddiness, twitching, irritability, convulsions, coma, decreased BV and BP if water is lost too dilutes their own ECF
46
potassium balance
important bc heavy regulation due to affect on resting membrane potential. hypokalemia and hyperkalemia can disrupt electrical stuff AND it acts as. buffer with H+ to balance overall pH
47
primary mechanism of potassium balance
renal, principal cells secret K+ in the DCT and collecting ducts. alters how much based on what is secreted. WHEN TOO HIGH typa A cells can reabsorb K+ when levels are TOO LOW so kidneys are limited in reabsorption capability
48
potassium secretion depends on
plasma concentration and aldosterone
49
plasma concentration with potassium balance
high ECF K+ concentrations drive excess K+ into principal cells, so increased secretion/excretion of K+, low ECF K+ concentrations promotes reabsorption
50
aldosterone with potassium balance
stimulates K+ secretion, adrenal cortex secretes aldosterone when K+ and ECF conc is high. has limited affect with large shifts in Na and volume concentrations that do not effect K+ overall. renal mechanisms will preserve desirable K+