Ch 4: Genes Flashcards

(46 cards)

1
Q

Central dogma

A

Source, order, and function of all genetic information 

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2
Q

Characteristics of central dogma

A

-DNA replicates and transcribes
-MRNA is a chemical messenger of information
-MRNA is translated into proteins

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3
Q

Proteins structure

A

Amino acids

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4
Q

Primary structure of proteins

A

Ala-leu-cys-met

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5
Q

Secondary structure of proteins

A

A. Alpha helix
B. Beta pleated sheet

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6
Q

Tertiary structure of proteins

A

Cross-links between our groups

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7
Q

Quaternary structure of proteins

A

Coils

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8
Q

Globular proteins

A

• spherical
-Insulin
-Hemoglobin
-Enzymes
-Antibodies

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9
Q

Fibrous proteins

A

• long, thin fibers
-Hair
-Wool
-Skin
-Nails

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10
Q

Definition of denaturation

A

Disruption of secondary tertiary and quaternary proteins by heat, acids, heavy metals, agitation

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11
Q

Examples of denaturation

A

-Heat cauterizing blood
-Hard boiling an egg
-Curling hair/straightening hair
-Heating milk to make yogurt

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12
Q

Purine bases

A

Adenine and guanine

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13
Q

Pyrimidines bases

A

Thymine and cytosine

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14
Q

Properties of gene

A

-polarity
-Strandedness
-antiparallelelicity
-Complementarity

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15
Q

Replication

A

DNA to rna to protein

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16
Q

DNA polymerization

A

Nucleotides bond together by dehydration reaction

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17
Q

Transcription

A

RNA uses dna that only reads individual genes

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18
Q

Gene expression

A

RNA transcription, proteins synthesis, regulation of expression, eukaryotic, and prokaryotic

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19
Q

Eukaryotic characteristics

A

-chromosomes are similar (linear)
-2 copies: diploid
-Positively charged and double stranded
-identical polymerization
Double stranded helix is extremely long

20
Q

Prokaryotic characteristics

A

-Single copy: haploid
-Histone like proteins
-no nucleus
-Identical, polymerization, one origin

21
Q

RNA

A

Ribonucleic acid
-Replication-> DNA-> transcribes-> RNA

22
Q

Gene

A

Sequence of DNA

23
Q

Genome

A

Collection of jeans= organism

24
Q

Genotype

A

Specific gene type

25
Phenotype
Physical and observable traits for genotype
26
Is the shape of a protein important
Yes, because it could change its function
27
What is the first process in central dogma?
Replication
28
MRNA
Blueprint for how proteins are made
29
RRNA
Ribosomal RNA part of ribosome
30
TRNA
Transfer RNA functions as helper to bring amino acids to ribosomes
31
Mutations
Deletion, duplication, inversion, translocation
32
Fixing mutations
Substitute, insertion, and deletion
33
Silent mutation
Change in mRNA sequence, which doesn’t change the a.a sequence of proteins
34
Missense mutation
Change an mRNA sequence, which does change the a.a sequence of the protein
35
What is the condition to induce the LAC operon?
High lactose, low glucose
36
Chromosome structures
Coil histones Coil around coil (chromatin) Coil chromatin (nucleosome) Super coiled structure (chromosome)
37
Extra nuclear DNA (5%)
Most common mitochondria and chloroplast are donated from Mom
38
Bacteria, prokaryotes
-histone like proteins (Hu) -Have single copy: haploid -have circular DNA -Have extra DNA: plasmids -conjunction: gene transfer
39
Conjunction
Gene transfer F-plasmids
40
Resistance, plasmids
Resistant to penicillin other medications
41
Bacteriosin plasmids
Kill is competition
42
Virulence plasmids
Ability to become pathogenic
43
Characteristics of a nucleotide
Sugar, phosphate, nitrogenous base
44
Properties of DNA
-Polar from nucleotide -anti-parallel -Complementary
45
Transponons
Movable DNA fragments that jump -Low frequency
46
How does bacteria defend themselves?
-bacterial immune system -Nucleic acid resistors